Biocatalysis for terpene-based polymers.

Zeitschrift Für Naturforschung. C, a Journal of Biosciences
Wissam FarhatPer-Olof Syrén

Abstract

Accelerated generation of bio-based materials is vital to replace current synthetic polymers obtained from petroleum with more sustainable options. However, many building blocks available from renewable resources mainly contain unreactive carbon-carbon bonds, which obstructs their efficient polymerization. Herein, we highlight the potential of applying biocatalysis to afford tailored functionalization of the inert carbocyclic core of multicyclic terpenes toward advanced materials. As a showcase, we unlock the inherent monomer reactivity of norcamphor, a bicyclic ketone used as a monoterpene model system in this study, to afford polyesters with unprecedented backbones. The efficiencies of the chemical and enzymatic Baeyer-Villiger transformation in generating key lactone intermediates are compared. The concepts discussed herein are widely applicable for the valorization of terpenes and other cyclic building blocks using chemoenzymatic strategies.

References

Jan 16, 2003·Journal of the American Chemical Society·Stephen G BellZihe Rao
Nov 11, 2003·Biomacromolecules·Ann-Christine Albertsson, Indra K Varma
Sep 9, 2004·Chemical Reviews·G-J ten BrinkR A Sheldon
Nov 19, 2004·Journal of the American Chemical Society·Jayme N Carter-Franklin, Alison Butler
Mar 14, 2007·Current Opinion in Chemical Biology·Rainer StuermerKurt Faber
Apr 3, 2009·Journal of the American Chemical Society·Scott A SnyderRitu Gupta
Aug 14, 2009·Nature·Alison Butler, Moriah Sandy
Nov 23, 2011·Angewandte Chemie·Eric Oldfield, Fu-Yang Lin
Jul 12, 2012·Journal of the American Chemical Society·Karavadhi Surendra, E J Corey
Oct 16, 2012·Biomacromolecules·Jihoon ShinMarc A Hillmyer
Nov 2, 2012·Journal of the American Chemical Society·Michel SchalkLaurent Daviet
Jan 17, 2013·Chembiochem : a European Journal of Chemical Biology·Feifei RenRey-Ting Guo
Feb 19, 2013·Chembiochem : a European Journal of Chemical Biology·Miriam SeitzBernhard Hauer
Jan 30, 2014·Annual Review of Plant Biology·Jiachen ZiReuben J Peters
Feb 7, 2014·Annual Review of Plant Biology·Ramesha ThimmappaAnne Osbourn
Dec 17, 2014·Nature Chemical Biology·Stephan C HammerBernhard Hauer
Mar 20, 2015·Biotechnology and Bioengineering·Xun Zhuang, Joe Chappell
Sep 10, 2015·Angewandte Chemie·Christine GallyBernhard Hauer
Jun 16, 2016·Nature Communications·O HauensteinA Greiner
Oct 21, 2016·Nature·Nobutaka KatoStuart L Schreiber
Nov 20, 2016·Angewandte Chemie·Patrick RabeJeroen S Dickschat
Dec 16, 2016·Nature·Yunqing ZhuCharlotte K Williams
Dec 20, 2016·Current Opinion in Chemical Biology·Yonghua WangFrank Hollmann
Dec 20, 2016·Nature Chemical Biology·Ridao ChenFei Sun
Feb 7, 2017·Nature Chemical Biology·Sherif I ElshahawiShanteri Singh
Aug 5, 2017·ChemSusChem·Steffen RothVolker Sieber
Aug 26, 2017·Chemical Reviews·David W Christianson
Sep 13, 2017·Chembiochem : a European Journal of Chemical Biology·Lisa C KühnelBernhard Hauer
Oct 6, 2017·Chembiochem : a European Journal of Chemical Biology·Adam ErikssonPer-Olof Syrén
Nov 28, 2017·Biotechnology Advances·Kathleen BalkeUwe T Bornscheuer
Mar 14, 2018·Biochemistry·Hanan L MessihaNigel S Scrutton
Mar 25, 2018·Angewandte Chemie·JiaJia DongWuyuan Zhang
Apr 28, 2018·Journal of the American Chemical Society·Maho MoritaEric W Schmidt
Sep 28, 2018·Scientific Reports·Aitor Hernandez-OrtegaNigel S Scrutton

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Citations

Feb 11, 2019·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Uwe T Bornscheuer
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maksim Nikulin, Vytas Švedas

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