PMID: 8581772Sep 1, 1995Paper

Biochemical and anthropometric characterization of morbid obesity in a large Utah pedigree

Obesity Research
S C HuntT D Adams

Abstract

A Utah family with morbid obesity was extended to include 122 persons in four generations for the purpose of characterizing anthropometric and biochemical variables in family members with and without morbid obesity. Seventy-seven subjects had blood drawn for biochemical analyses. Of the 77 subjects, 12 were morbidly obese (> or = 44.5 kg or 100 pounds overweight), 20 were between 22.5-45.4 kg (50 and 99 pounds) overweight and 45 were less than 22.5 kg (50 pounds) overweight. Sixty-two randomly-ascertained controls were used for comparisons of age- and gender-adjusted study variables. Morbidly obese subjects had mean body mass indices (BMI) of 41.0 kg/m2 (62 kg over ideal weight) compared to 25.3 kg/m2 (10 kg overweight) in the < 22.5 kg family members (p < 0.001). The < 22.5 kg family members had lower BMI than the random controls (27.6 kg/m2, p < 0.05), indicating clear bimodality of obesity within the pedigree. Percent body fat from bioelectrical impedance was 35% versus 24% in the morbidly obese and the < 22.5 kg subjects, respectively. Idealbody weight was similar among the three pedigree weight groups. Hip and waist circumferences were much larger in the morbidly obese and the waist-to-hip ratio remained significantly grea...Continue Reading

Associated Clinical Trials

References

Feb 1, 1992·The American Journal of Clinical Nutrition·R J Kuczmarski
Jan 1, 1986·Journal of Chronic Diseases·S C HuntG K Barlow
Jan 23, 1986·The New England Journal of Medicine·A J StunkardF Schulsinger
Oct 1, 1983·Lancet·J Yudkin
Jan 1, 1993·Annual Review of Nutrition·C Bouchard, L Pérusse
Jul 1, 1993·Obesity Research·T D AdamsR R Williams

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Citations

Jul 16, 2010·Journal of Lipid Research·Bela F AsztalosPeter J Havel
Apr 11, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·J HebebrandH Remschmidt

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