Biochemical and full genome sequence analyses of clinical Vibrio cholerae isolates in Mexico reveals the presence of novel V. cholerae strains

Microbes and Infection
José Alberto Díaz-QuiñonezJosé Ernesto Ramírez-González

Abstract

The first week of September 2013, the National Epidemiological Surveillance System identified two cases of cholera in Mexico City. The cultures of both samples were confirmed as Vibrio cholerae serogroup O1, serotype Ogawa, biotype El Tor. Initial analyses by PFGE and by PCR-amplification of the virulence genes, suggested that both strains were similar, but different from those previously reported in Mexico. The following week, four more cases were identified in a community in the state of Hidalgo, located 121 km northeast of Mexico City. Thereafter a cholera outbreak started in the region of La Huasteca. Genomic analyses of the four strains obtained in this study confirmed the presence of Pathogenicity Islands VPI-1 and -2, VSP-1 and -2, and of the integrative element SXT. The genomic structure of the 4 isolates was similar to that of V. cholerae strain 2010 EL-1786, identified during the epidemic in Haiti in 2010.

References

Jan 16, 2003·Nucleic Acids Research·Miguel Angel Reyes-LópezKenneth L Beattie
Nov 22, 2011·Emerging Infectious Diseases·Aleisha R ReimerUNKNOWN V. cholerae Outbreak Genomics Task Force
Nov 22, 2011·Emerging Infectious Diseases·Deborah TalkingtonPeter Gerner-Smidt
Apr 21, 2012·Journal of Clinical Microbiology·Munirul AlamAlejandro Cravioto
Jul 4, 2012·Lancet·Jason B HarrisStephen B Calderwood
Oct 10, 2013·The American Journal of Tropical Medicine and Hygiene·Brendan R Jackson The Cholera Serosurvey Working Group
Jun 25, 2014·Proceedings of the National Academy of Sciences of the United States of America·Munirul AlamAlejandro Cravioto
Nov 2, 2014·Genome Announcements·José Alberto Díaz-QuiñonezJosé Ernesto Ramírez-González

❮ Previous
Next ❯

Citations

Jul 3, 2018·FEMS Microbiology Letters·Beatriz Casasola-RodríguezMaría Teresa Orta de Velásquez
Jun 15, 2016·Infection and Immunity·Karla J F SatchellFitnat H Yildiz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Related Papers

MMWR. Morbidity and Mortality Weekly Report
Alberto Díaz-QuiñonezCenters for Disease Control and Prevention (CDC)
Genome Announcements
José Alberto Díaz-QuiñonezJosé Ernesto Ramírez-González
Emerging Infectious Diseases
Vincent R HillRobert V Tauxe
© 2021 Meta ULC. All rights reserved