Biochemical and physiological responses in liver and muscle of rainbow trout after long-term exposure to propiconazole

Ecotoxicology and Environmental Safety
Zhi-Hua LiTomas Randak

Abstract

In this study, the chronic toxic effects of PCZ, a triazole fungicide commonly present in surface and ground water, on morphological indices, ROS generation and RNA/DNA ratio in liver and white muscle of rainbow trout were investigated. Fish were exposed at sublethal concentrations of PCZ (0.2, 50 and 500 microg L(-1)) for 7, 20 and 30d. Compared with the control, there were significant lower CF and HSI in fish exposed at the highest concentration of PCZ. ROS levels in both tissues increased significantly at higher PCZ concentrations (50 and 500 microg L(-1)) after 20 d and above, as well as in muscle of fish exposed at lowest PCZ concentration (0.2 microg L(-1)) after 30 d. The hepatic antioxidant enzymes (SOD and CAT) activities were induced significantly at higher concentrations (50, 500 microg L(-1)) of PCZ after 20 d and at 50 microg L(-1) after 30 d. Additional, hepatic SOD activity was significantly induced at 0.2 microg L(-1) after 30 d. Compared with the hepatic antioxidant enzymes activities in fish exposed to 50 microg L(-1) of PCZ, there was a decreasing trend in those exposed to 500 microg L(-1) after 30 d exposure. However, both the antioxidant enzymes activities were significantly inhibited in muscle of fish expo...Continue Reading

References

Jan 1, 1989·Archives of Environmental Contamination and Toxicology·M J McKeeD R Buckler
Sep 3, 1996·Proceedings of the National Academy of Sciences of the United States of America·P W HochachkaS C Land
Feb 5, 1999·Bulletin of Environmental Contamination and Toxicology·R James, K Sampath
Jul 7, 1999·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·L GatéH Tapiero
Apr 12, 2000·Neurotoxicology and Teratology·A S DriverW R Mundy
Dec 1, 2001·Free Radical Biology & Medicine·J Nordberg, E S Arnér
Apr 25, 2003·Archives of Environmental Contamination and Toxicology·R A Khan
May 14, 2003·Ecotoxicology and Environmental Safety·Antonia Concetta EliaLuciana Mantilacci
Jun 12, 2003·The Science of the Total Environment·Suwarna PandeySheikh Raisuddin
Nov 1, 2005·Aquatic Toxicology·Karl FentDaniel Caminada
Apr 29, 2006·The Science of the Total Environment·Luisa Eugenia CastilloEfrain Solis
Jul 24, 2007·Ecotoxicology and Environmental Safety·Justyna Kopecka, Janusz Pempkowiak
Apr 19, 2008·The Science of the Total Environment·Senka TerzićDalila Jabucar
Sep 26, 2008·The Science of the Total Environment·Johnny GasperiRégis Moilleron
May 5, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Yu-Liang DongXiao-Hu Zhao
Jun 9, 2009·Ecotoxicology and Environmental Safety·P Kavitha, J Venkateswara Rao
Feb 1, 2003·Environmental Toxicology and Pharmacology·Ron van der OostNico P E Vermeulen

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Citations

Jun 28, 2011·Journal of Agricultural and Food Chemistry·Chao Wang, Ying Li
Oct 15, 2011·Molecular & Cellular Proteomics : MCP·Zhi-Hua LiTomas Randak
Aug 14, 2012·Bulletin of Environmental Contamination and Toxicology·Jinshou LiChonggang Wang
Jul 14, 2012·Aquatic Toxicology·Jinshou LiChonggang Wang
Jul 23, 2011·Chemosphere·Olha I KubrakVolodymyr I Lushchak
Jul 6, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Zhi-Hua LiTomas Randak
Apr 19, 2012·Environmental Toxicology and Chemistry·Daniel Gutiérrez-PraenaAna M Cameán
Jun 16, 2015·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Amit Kumar SinhaGudrun De Boeck
Oct 24, 2014·Environmental Science and Pollution Research International·Mehmet YilmazMustafa Canli
Dec 16, 2016·Integrated Environmental Assessment and Management·Ellen M MihaichKeith Solomon
Jul 1, 2020·Environmental Science and Pollution Research International·Aysel Alkan Uçkun, Özden Barım Öz
Jul 26, 2019·Environmental Science and Pollution Research International·Jéssica ValadasAngelo Piato
Sep 6, 2020·The Science of the Total Environment·Sofie SvanholmCecilia Berg

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