Biochemical and physiological responses induced in Mytilus galloprovincialis after a chronic exposure to salicylic acid

Aquatic Toxicology
Rosa FreitasCaterina Faggio

Abstract

A vast variety of substances currently reaches the aquatic environment, including newly developed chemicals and products. Lack of appropriate analytical methods for trace determinations in aquatic ecosystem compartments and lack of information regarding their toxicity explains existing regulation gaps. However, suspicion of their toxicity assigned them as Contaminants of Emerging Concern (CECs). Among CECs are Pharmaceuticals including Salicylic Acid (SA), which is the active metabolite of acetylsalicylic acid (ASA; aspirin). The aim of the present study was to evaluate the potential effects of SA on the mussel Mytilus galloprovincialis. For this, organisms were exposed for 28 days to different concentrations of SA (0.005; 0.05; 0.5 and 5 mg/L), resembling low to highly polluted sites, after which different physiological and biochemical parameters were evaluated to assess organism's respiration rate, neurotoxic, metabolic and oxidative stress status. Our results clearly showed that SA strongly reduced the respiration capacity of mussels. Also, SA inhibited the activity of superoxide dismutase (SOD) and catalase (CAT) enzymes, but increased the activity of glutathione peroxidase (GPx) and glutathione-S-transferases (GSTs), which...Continue Reading

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Nov 12, 2019·Journal of Fish Diseases·Antonio BoxJosé María Valencia
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Oct 11, 2020·Ecotoxicology and Environmental Safety·Haitham G Abo-Al-Ela, Caterina Faggio
Apr 21, 2021·Environmental Toxicology and Pharmacology·Ângela AlmeidaRosa Freitas
Jun 22, 2021·Journal of Water and Health·Sabrine AfsaHedi Ben Mansour
Jul 27, 2021·Environmental Toxicology and Pharmacology·Rosa FreitasCaterina Faggio
Sep 21, 2021·International Journal of Phytoremediation·Ons BachaSamir Touaylia
Oct 2, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Kishore DharaCaterina Faggio

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