Biochemical assessment of patients following ketogenic diets for epilepsy: Current practice in the UK and Ireland

Epilepsia Open
N E SchoelerKetogenic Dietitians Research Network (KDRN)

Abstract

Biochemical assessment is recommended for patients prior to initiating and following a ketogenic diet (KD). There is no published literature regarding current practice in the UK and Ireland. We aimed to explore practice in comparison with international guidelines, determine approximate costs of biochemical testing in KD patients across the UK and Ireland, and promote greater consistency in KD services nationally. A survey was designed to determine the biochemical tests requested for patients at baseline, 3, 6, 12, 18, and 24 months + on KD. The survey was circulated to 39 centers across the UK and Ireland. Sixteen centers completed the survey. Full blood count, electrolytes, calcium, liver function tests (LFTs), lipid profile, and vitamin D were requested at all centers at baseline, in keeping with international guidelines. Bicarbonate, total protein, and urinalysis were less consistently requested. Magnesium and zinc were requested by all centers, despite not being specifically recommended for pre-diet evaluation in guidelines. Urea and electrolyte profiles and some LFTs were consistently requested at follow-up, in accordance with guidelines. Other LFTs and renal tests, full blood count, lipid profile, acylcarnitine profile, s...Continue Reading

References

Aug 24, 1979·Calcified Tissue International·T J HahnD C DeVivo
Jun 14, 2000·Seizure : the Journal of the British Epilepsy Association·G MagrathW Whitehouse
Apr 19, 2003·Epilepsia·A G Christina BergqvistVirginia A Stallings
Jan 24, 2007·Epilepsia·A G Christina BergqvistVirginia A Stallings
Aug 28, 2007·Developmental Medicine and Child Neurology·Joerg Klepper, Baerbel Leiendecker
May 6, 2008·Lancet Neurology·Elizabeth G NealJ Helen Cross
Nov 26, 2008·Pediatric Neurology·Ilana M BankAndrew S Mackie
May 28, 2011·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·S S ChristodoulidesJ H Cross
Mar 1, 2012·Pediatric Cardiology·Naga S SirikondaCharles J Mullett
Nov 23, 2016·Biological Trace Element Research·Nur ArslanOrkide Guzel
Aug 21, 2019·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·V J WhiteleyUNKNOWN Ketogenic Dietitians Research Network (KDRN)

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Citations

Sep 17, 2020·Nutrients·Francesc Josep García-GarcíaGlòria Garrabou

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