Biochemical changes in lysogenic Bacillus stearothermophilus after bacteriophage induction.

Journal of Bacteriology
N E WELKER, L L CAMPBELL

Abstract

Welker, N. E. (University of Illinois, Urbana), and L. Leon Campbell. Biochemical changes in lysogenic Bacillus stearothermophilus after bacteriophage induction. J. Bacteriol. 90:1129-1137. 1965.-Cultures of Bacillus stearothermophilus 1503-4R (TP-1) continued to grow at an unaltered rate after induction with mitomycin C (MC). MC-induced cultures exhibited a 2.5-fold increase in cell number before lysis occurred. Prior to lysis, cells were observed to elongate and to contain areas of lesser density. Protein synthesis was slightly inhibited in MC- or ultraviolet light (UV)-induced cultures for a period of 5 to 10 min, and then proceeded at a rate identical to that in the noninduced culture. Ribonucleic acid (RNA) synthesis was not affected by MC induction. UV induction caused RNA synthesis to occur in two stages: in the first stage, the rate of RNA synthesis was one-third that observed in the noninduced culture and lasted for a period of 15 min; the second stage of RNA synthesis then proceeded at a rate identical to that in the noninduced culture. The synthesis of deoxyribonucleic acid (DNA) in an MC- or UV-induced culture occurred in two stages. In the first stage, DNA synthesis in induced cultures occurred at a rate of one-hal...Continue Reading

References

Nov 1, 1952·Biochimica Et Biophysica Acta·L SIMINOVITCH, S RAPKINE
Dec 1, 1953·Bacteriological Reviews·A LWOFF
Mar 1, 1962·Journal of Molecular Biology·N SUEOKA, T Y CHENG
Jun 1, 1960·Analytical Biochemistry·J D MANDELL, A D HERSHEY

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Citations

Mar 1, 1968·The Journal of Applied Bacteriology·L L Campbell, B Pace
Jun 1, 1967·Journal of Virology·L N Egbert, H K Mitchell
Oct 1, 1966·Journal of Bacteriology·L L CampbellJ R Postgate
Feb 1, 1975·Applied Microbiology·I Epstein, L L Campbell
Oct 1, 1967·Journal of Bacteriology·N E Welker, L L Campbell
Jan 1, 1966·Journal of Bacteriology·G F Saunders, L L Campbell
Aug 8, 2021·Microorganisms·Beata ŁubkowskaPiotr M Skowron

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