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Biochemical changes in subacute mycotoxicosis induced by T-2 toxin in rats

Toxicology

Dec 1, 1986

L V KravchenkoL I Avrenyeva

Abstract

The intragastric administration to male Wistar rats of T-2 toxin at 1-1.3 mg/kg body weight for 7 days caused a sharp decrease in the liver activity of lysosomal enzymes: beta-galactosidase, beta-N-acetylglucosaminidase, alpha-mannosidase, cathepsins A, B, C and D and in the activity of...read more

Mentioned in this Paper

Metabolic Process, Cellular
Carboxylesterase
Enzymes, antithrombotic
Mushroom Poisoning
T-2 Toxin
Glucuronosyltransferase
August Rats
Cytochrome P450
Weighing Patient
Sesquiterpenes
Paper Details
References
  • References9
  • Citations7
1
  • References9
  • Citations7
1

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Biochemical changes in subacute mycotoxicosis induced by T-2 toxin in rats

Toxicology

Dec 1, 1986

L V KravchenkoL I Avrenyeva

PMID: 3798460

DOI: 10.1016/0300-483x(86)90094-6

Abstract

The intragastric administration to male Wistar rats of T-2 toxin at 1-1.3 mg/kg body weight for 7 days caused a sharp decrease in the liver activity of lysosomal enzymes: beta-galactosidase, beta-N-acetylglucosaminidase, alpha-mannosidase, cathepsins A, B, C and D and in the activity of...read more

Mentioned in this Paper

Metabolic Process, Cellular
Carboxylesterase
Enzymes, antithrombotic
Mushroom Poisoning
T-2 Toxin
Glucuronosyltransferase
August Rats
Cytochrome P450
Weighing Patient
Sesquiterpenes

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Cytochrome P450 (CYP450) are a family of enzymes involved in two major processes, such as the synthesis of fatty acids, steroids, and biles acids, and the metabolism of toxins and drugs. Discover the latest research on the Mechanisms of CYP450 enzymes here.

Related Papers

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

Comparative effects of T-2 toxin and diacetoxyscirpenol on drug metabolizing enzymes in rat tissues

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research AssociationApril 1, 1989
P GaltierG Larrieu
Toxicon : Official Journal of the International Society on Toxinology

Cerebral toxicity of the trichothecene toxin T-2, of the products of its hydrolysis and of some related toxins

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F BergmannB Yagen
Paper Details
References
  • References9
  • Citations7
1
  • References9
  • Citations7
1
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