Biochemical characterization of the virus causing leukoencephalitis and arthritis in goats

The Journal of General Virology
J E ClementsL C Cork

Abstract

Goat leukoencephalitis-arthritis virus (GLV) has the density of a retrovirus in sucrose and contains an endogenous RNA-dependent DNA polymerase (reverse transcriptase). The virion reverse transcriptase utilizes the synthetic RNA template poly(rA). (dT)12 but not the synthetic DNA template poly(dA). (dT)12. A high mol. wt. RNA similar in size to visna virus RNA was isolated from 3H-uridine-labelled virions. The major structural protein of GLV has the same mol. wt. as that of visna virus. From these data the GLV appears to be a retrovirus.

Citations

Nov 1, 1984·Veterinary Research Communications·F K Al-Ani, J G Vestweber
Oct 1, 1985·Journal of Comparative Pathology·S Kennedy-StoskopfJ D Strandberg
Sep 11, 2002·Cytokine & Growth Factor Reviews·Yoichiro Iwakura
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Feb 26, 1999·International Reviews of Immunology·U Müller-LadnerS Gay
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