Apr 15, 1976

Biochemical differences between the MB and MM isoenzymes of creatine kinase

Clinica Chimica Acta; International Journal of Clinical Chemistry
P C Wong, A F Smith

Abstract

The biochemical properties of partially purified preparations of human myocardial MB and MM iosenzymes of creatine kinase have been compared with one another. Differences in substrate affinity, behaviour with inhibitors, and heat denaturation have been demonstrated. It is doubtful if the differences we have shown are sufficiently great to form the basis of a practical routine procedure for measuring serum levels of the MB isoenzyme.

  • References4
  • Citations15

References

  • References4
  • Citations15

Citations

Mentioned in this Paper

Macro-Creatine Kinase
Hot Temperature
Myocardium
Cardiomyopathies
Striadyne
Hydrogen-Ion Concentration
Adenosine Triphosphate, Chromium Ammonium Salt
Enzyme Activation
Magnesium
Alloenzymes

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