Biochemical markers of bone remodeling

The American Journal of the Medical Sciences
M Kleerekoper

Abstract

Bone formation and resorption (or bone turnover) are reflected by levels in blood and urine of various enzymes from bone cells, byproducts of bone matrix synthesis, or breakdown products of bone. These biochemical markers provide information about projected rates of bone loss and can be useful in assessing the effectiveness of antiresorptive therapy for osteoporosis. Biochemical markers provide adjunctive information to bone density measurements, and may be independent predictors of fracture risk. For clinical use, combining markers of resorption and formation should give better information than a single marker.

References

Jan 1, 1990·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P D DelmasP A Price
Nov 1, 1995·Scandinavian Journal of Clinical and Laboratory Investigation·M Panteghini, F Pagani

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Citations

Oct 5, 2013·Blood Cells, Molecules & Diseases·M BaldiniM D Cappellini
Nov 11, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·H EnglerW F Riesen
Jul 23, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Pierre DelanayeEtienne Cavalier
Jun 23, 2005·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·S NarisawaJ L Millán
Aug 6, 1999·Obstetrical & Gynecological Survey·N B Watts

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