PMID: 9192513Jul 1, 1997Paper

Biochemical markers of bone turnover in Camurati-Engelmann disease: a report on four cases in one family

Calcified Tissue International
M V HernándezJ Muñoz-Gómez

Abstract

Moderate increases in "classical" biochemical markers of bone turnover have been described only in some patients with Camurati-Engelmann disease. However, the determination of the following "new" markers has not been previously performed: serum osteocalcin (BGP), bone alkaline phosphatase (BAP), carboxyterminal propeptide of type I procollagen (PICP), aminoterminal propeptide of type I procollagen (PINP), tartrate-resistant acid phosphatase (TRAP), telopeptide carboxyterminal of type I collagen (ICTP), urinary pyridinoline (PYR), crosslinked N-telopeptides of type I collagen (NTX), and Crosslaps (CL). Such a determination may improve the evaluation of the disease activity. To evaluate the usefulness of biochemical markers of bone turnover reflecting Camurati-Engelmann disease activity we measured the levels of all these markers in four affected patients. The results were compared with bone scintigraphic indices of disease activity. Except for PICP and TRAP, bone formation and resorption markers were abnormal in all patients and were related to bone scan indices of disease activity. Among the markers of bone formation PINP, BAP, and BGP showed the highest values, whereas NTX and CL were the most sensitive markers of bone resorpt...Continue Reading

Citations

Dec 21, 2007·Journal of Bone and Mineral Metabolism·Kousuke IbaToshihiko Yamashita
Jan 22, 2005·Clinical Rheumatology·Glaucio R W CastroIbsen Coimbra
Nov 26, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Y NishiB D Gelb
May 5, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Michael P WhyteSteven Mumm
Oct 30, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Shiguang LiuSusan C Schiavi
Aug 27, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S HerreraA Diez-Perez
Jan 29, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Peter HughesTim Cundy
Mar 2, 2017·Cold Spring Harbor Perspectives in Biology·Elena Gallo MacFarlaneEileen M Shore
Mar 24, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Núria GuañabensMichael P Whyte
Dec 14, 2016·Molecular Medicine Reports·Yong ChenJianda Zhou
Sep 8, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Qian LiWeibo Xia
Sep 19, 2006·Genes & Development·Stuart H Ralston, Benoit de Crombrugghe

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