PMID: 39348Oct 1, 1979

Biochemistry and the schizophrenias

Southern Medical Journal
J SMYTHIES

Abstract

This paper reviews the present status of the transmethylation and the dopamine hypotheses of schizophrenia and presents recent data on the definitive identification and measurement of the endogenous hallucinogen, dimethyltryptamine (DMT) in human cerebrospinal fluid and urine. Elevated levels are found in some cases of schizophrenia and of liver disease. Evidence is discussed showing that DMT may be a normal neuroregulatory agent which is responsive to stress or emotional reactions.

References

May 31, 1996·American Journal of Medical Genetics·H BeckmannG Stöber
Jan 1, 1995·European Archives of Psychiatry and Clinical Neuroscience·G StöberH Beckmann
Jan 1, 1987·Progress in Neuro-psychopharmacology & Biological Psychiatry·T A Ban
Mar 31, 2000·Comprehensive Psychiatry·P BräunigI Börner
Feb 19, 1998·Schizophrenia Research·J Ciprian-Ollivier, M G Cetkovich-Bakmas
Apr 1, 1997·Acta Psychiatrica Scandinavica·B Pfuhlmann, G Stöber
Jun 5, 2001·Medical Hypotheses·J Krøll

Related Concepts

Urine
Schizophrenia
Cerebrospinal Fluid
Pedameth
Liver Diseases
Dopamine Measurement
Methylation
Dopamine
Neurohormones
Intropin

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