Biocompatibility and antibacterial activity of the Adathoda vasica Linn extract mediated silver nanoparticles

Microbial Pathogenesis
M LathaNarayanan Marimuthu Prabhu

Abstract

The aim of this study is to investigate the biocompatibility and anti-Vibrio efficacy of green synthesized silver nanoparticles (AgNPs) using an aqueous leaf extract of Adathoda vasica (A. vasica). The green synthesized silver nanoparticles were characterized by UV-vis, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). A. vasica AgNPs showed significant antibacterial activity against Vibrio parahaemolyticus in agar bioassay and well diffusion method. Further, nanoparticles interactions with bacteria and its antibacterial activity were confirmed by CLSM analysis. In vivo evaluation results confirmed that synthesized A. vasica AgNPs had good antibacterial efficacy and also nontoxic to the Artemia nauplii.

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Citations

Feb 18, 2018·Journal of Nanobiotechnology·Khwaja Salahuddin SiddiqiRifaqat A K Rao
Jun 9, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sin-Yeang TeowKamyar Shameli
Sep 17, 2019·Dose-response : a Publication of International Hormesis Society·Rida ZainabMuhammad Riaz
Dec 2, 2020·Journal of Functional Biomaterials·Ekaterina O Mikhailova
Jul 12, 2017·Journal of Photochemistry and Photobiology. B, Biology·Chinnasamy BalalakshmiGiovanni Benelli
Jun 10, 2018·Ecotoxicology and Environmental Safety·Chinnaperumal KamarajPachiappan Perumal

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