Bioconversion of grape must into modulated gluconic acid production by Aspergillus niger ORS-4.410

Journal of Applied Microbiology
O V Singh, R P Singh

Abstract

Analysis of regulators for modulated gluconic acid production under surface fermentation (SF) condition using grape must as the cheap carbohydrate source, by mutant Aspergillus niger ORS-4.410. Replacement of conventional fermentation condition by solid-state surface fermentation (SSF) for semi-continuous production of gluconic acid by pseudo-immobilization of A. niger ORS-4.410. Grape must after rectification was utilized for gluconic acid production in batch fermentation in SF and SSF processes using mutant strain of A. niger ORS-4.410. Use of rectified grape must led to the improved levels of gluconic acid production (80-85 g l(-1)) in the fermentation medium containing 0.075% (NH4)2HPO4; 0.1% KH2PO4 and 0.015% MgSO4.7H2O at an initial pH 6.6 (+/-0.1) under surface fermentation. Gluconic acid production was modulated by incorporating the 2% soybean oil, 2% starch and 1% H2O2 in fermentation medium at continuously high aeration rate (2.0 l min(-1)). Interestingly, 95.8% yield of gluconic acid was obtained when A. niger ORS-4.410 was pseudo-immobilized on cellulose fibres (bagasse) under SSF. Four consecutive fermentation cycles were achieved with a conversion rate of 0.752-0.804 g g(-1) of substrate into gluconic acid under S...Continue Reading

References

Nov 1, 1993·Current Genetics·F B WitteveenJ Visser
May 3, 2000·International Journal of Food Microbiology·M BekersP Zikmanis
Apr 26, 2001·Journal of Industrial Microbiology & Biotechnology·T Roukas
Mar 26, 2003·Applied Microbiology and Biotechnology·S AnastassiadisC Wandrey

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Citations

May 26, 2007·Applied Microbiology and Biotechnology·Om V Singh, Raj Kumar
Jul 14, 2010·Letters in Applied Microbiology·C DowdellsD M Mousdale
Apr 24, 2014·Critical Reviews in Biotechnology·Saúl AlonsoMario Díaz
Sep 26, 2020·Applied Microbiology and Biotechnology·Li SunLong Liu

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