Biodegradable dendrimers for drug delivery

Materials Science & Engineering. C, Materials for Biological Applications
Da Huang, Decheng Wu

Abstract

Dendrimers, as a type of artificial polymers with unique structural features, have been extensively explored for their applications in biomedical fields, especially in drug delivery. However, one important concern about the most commonly used dendrimers exists - the nondegradability, which may cause side effects induced by the accumulation of synthetic polymers in cells or tissues. Therefore, biodegradable dendrimers incorporating biodegradability with merits of dendrimers such as well-defined architectures, copious internal cavities and surface functionalities, are much more promising for developing novel nontoxic drug carriers. Herein, we review the recent advances in design and synthesis of biodegradable dendrimers, as well as their applications in fabricating drug delivery systems, with the aim to provide researchers in the related fields a good understanding of biodegradable dendrimers for drug delivery.

Citations

Jul 25, 2019·Luminescence : the Journal of Biological and Chemical Luminescence·Hojjat Samareh FekriNazanin Ziasistani
Jan 19, 2020·Cancers·Jonathan M PantshwaViness Pillay
May 13, 2020·Drug Delivery·Salma A FereigMona M A Abdel-Mottaleb
Jul 24, 2020·Expert Opinion on Drug Delivery·Johan KarlssonStephany Y Tzeng
Sep 20, 2020·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Haonan LiKui Luo
Jul 1, 2020·Expert Opinion on Drug Delivery·Susbin Raj WagleHani Al-Salami
Jul 30, 2019·Critical Reviews in Analytical Chemistry·Bruno Vincenzo Fiod RiccioMarlus Chorilli
Dec 12, 2019·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Danushika C ManatungaK M Nalin de Silva
Sep 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Søren Mejlsøe, Ashok Kakkar
Mar 12, 2020·Polymers·Imran AliJung-Chih Chen
Jul 25, 2019·Current Pharmaceutical Design·Vijay MishraNamita Giri
Dec 1, 2019·Biomolecules·Yuefei ZhuZhiqing Pang
Jan 29, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Beatriz Rossi Canuto de MenezesGilmar Patrocínio Thim
Jan 6, 2021·Pharmaceutics·Iman M AlfagihMariyam M Alfagih
Jul 9, 2020·Bioactive Materials·Mingze SunKazunori Hoshino
Apr 4, 2021·Biomolecules·Aikaterini BerdiakiDragana Nikitovic
Apr 27, 2021·Expert Opinion on Drug Delivery·Gabriel Silva Marques BorgesLucas Antônio Miranda Ferreira
May 29, 2021·International Journal of Nanomedicine·Sasmita SamalMamoni Dash
Jun 15, 2021·Frontiers in Bioengineering and Biotechnology·Xiaohan HuangWeiqiang Lin
Aug 29, 2019·ACS Omega·Rohini KanwarSurinder K Mehta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Current Opinion in Drug Discovery & Development
Mohammad Najlah, Antony D'Emanuele
Current Medicinal Chemistry
Maria Bryszewska, Barbara Klajnert
Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Adela ŠtimacRuža Frkanec
© 2022 Meta ULC. All rights reserved