Biodegradable miniplates (LactoSorb): long-term results in infant minipigs and clinical results

The Journal of Craniofacial Surgery
J WiltfangP Kessler

Abstract

Metallic plates are known for their passive intraosseous transmission in the growing skull. To avoid plate removal, resorbable material with strength comparable to that of metallic plates and predictable resorption would be desirable. This should be accomplished without causing inflammatory complications and foreign body reactions often seen with highly crystalline poly-L-lactic acid or pure polyglycolic acid implants. In an animal experiment in four young Göttingen minipigs, the resorbable poly-L-lactic acid/polyglycolic acid copolymer LactoSorb was tested previously. In addition to testing the mechanical properties, the process of degradation and sub- versus epi- or supraperiosteal application of the miniplate device LactoSorb was evaluated using a frontal cranioosteoplasty model. Furthermore, LactoSorb was used in 10 patients with craniosynostosis or craniofacial trauma. During degradation, the absorbable poly-L-lactic acid/polyglycolic acid miniplates acted like metal plates because they also displayed passive intraosseous transmission in the growing animal model. Degradation took 12 to 18 months and was not delayed by bony incorporation. Their mechanical properties proved to be sufficient in craniofacial surgery. Epiperios...Continue Reading

Citations

Aug 19, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Thomas RodtJoachim K Krauss
Feb 6, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Pat Ricalde, Jeffrey C Posnick
Apr 25, 2003·Plastic and Reconstructive Surgery·Constantin A Landes, Susanne Kriener
Jul 12, 2011·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Peter J Taub, Joshua A Lampert
Mar 26, 2014·National Journal of Maxillofacial Surgery·Rishi K BaliShivani Gaba
Apr 8, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Constantin LandesRobert Sader
Apr 10, 2010·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Siegfried JankHarri Happonen
Jan 6, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Petteri VäänänenSiegfried Jank
Jun 17, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Petteri VäänänenSiegfried Jank
Jun 22, 2007·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Ingo N G SpringerJörg Wiltfang
Jul 28, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Yoshimasa KitagawaKazuki Miyauchi
Sep 19, 2006·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Kevin Daniel KielyRichard C Edwards
Jan 21, 2006·International Journal of Oral and Maxillofacial Surgery·C E ZimmermannL B Kaban
Sep 13, 2005·International Journal of Oral and Maxillofacial Surgery·C E ZimmermannL B Kaban
Feb 28, 2015·Maxillofacial Plastic and Reconstructive Surgery·Young-Wook Park
Dec 28, 2016·The Journal of Craniofacial Surgery·Samuel GolpanianSeth R Thaller
Sep 13, 2012·Laboratory Animals·J ŠtembírekM Buchtová
Feb 6, 2016·Archives of Plastic Surgery·Hong Bae JeonSang Ah Oh
May 1, 2002·Annals of Plastic Surgery·W Tomasz MajewskiArturo Aguillon
Sep 10, 2002·The Journal of Craniofacial Surgery·Stefano SpanioMilomir Ninkovic
Oct 7, 2004·Plastic and Reconstructive Surgery·Barry L EppleyA Michael Sadove
Aug 26, 2006·Plastic and Reconstructive Surgery·Constantin A Landes, Alexander Ballon
Dec 2, 2010·The Journal of Craniofacial Surgery·Jang Hyun LeeHee Chang Ahn
Sep 27, 2005·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·C A LandesC Roth
Feb 8, 2006·Plastic and Reconstructive Surgery·Constantin A Landes, Alexander Ballon
Dec 24, 2013·The Open Biomedical Engineering Journal·Constantin LandesRaimund Jaeger
Oct 1, 2009·Craniomaxillofacial Trauma & Reconstruction·Mohammed E Elsalanty, David G Genecov
Jan 11, 2019·Journal of Cardiothoracic Surgery·Jonas RasmussenVibeke E Hjortdal

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioremediation (ASM)

Bioremediation is the treatment and removal of harmful pollutants or contaminants through the use of microorganisms. Discover the latest research here.

Related Papers

Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
J WiltfangH G Luhr
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
W BährE Wellens
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Maurice Y Mommaerts, Patrick F J Staels
Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
N B van BakelenR R M Bos
© 2021 Meta ULC. All rights reserved