Biodegradable toughened nanohybrid shape memory polymer for smart biomedical applications

Nanoscale
Arpan BiswasPralay Maiti

Abstract

A polyurethane nanohybrid has been prepared through the in situ polymerization of an aliphatic diisocyanate, ester polyol and a chain extender in the presence of two-dimensional platelets. Polymerization within the platelet galleries helps to intercalate, generate diverse nanostructure and improve the nano to macro scale self-assembly, which leads to a significant enhancement in the toughness and thermal stability of the nanohybrid in comparison to pure polyurethane. The extensive interactions, the reason for property enhancement, between nanoplatelets and polymer chains are revealed through spectroscopic measurements and thermal studies. The nanohybrid exhibits significant improvement in the shape memory phenomena (91% recovery) at the physiological temperature, which makes it suitable for many biomedical applications. The structural alteration, studied through temperature dependent small angle neutron scattering and X-ray diffraction, along with unique crystallization behavior have extensively revealed the special shape memory behavior of this nanohybrid and facilitated the understanding of the molecular flipping in the presence of nanoplatelets. Cell line studies and subsequent imaging testify that this nanohybrid is a super...Continue Reading

References

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Citations

May 16, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xin LiHong Tan
Dec 20, 2018·Journal of Biomedical Materials Research. Part a·Aparna ShuklaPralay Maiti
Apr 7, 2021·ACS Applied Materials & Interfaces·Sang Won LeeDacheng Ren
May 1, 2021·Polymers·Li JingchengRituparna Ghosh
Jul 29, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Liguo JinXiaolei Wang
Jul 24, 2020·Biomacromolecules·Bhingaradiya NutanSuresh K Jewrajka
May 28, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Arpan BiswasPralay Maiti

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Methods Mentioned

BETA
SMAs
X-ray
small angle neutron scattering
AFM
fluorescence microscopy
small
angle neutron scattering
small angle neutron scanning
SANS
NMR

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