PMID: 10224025May 1, 1999

Biodegradation of cyclohexylamine by Brevibacterium oxydans IH-35A

Applied and Environmental Microbiology
Hiroaki IwakiYoshie Hasegawa


A bacterial strain capable of growing on cyclohexylamine (CHAM) was isolated by using enrichment and isolation techniques. The strain isolated, strain IH-35A, was classified as a member of the genus Brevibacterium. The results of growth and enzyme studies are consistent with degradation of CHAM via cyclohexanone (CHnone), 6-hexanolactone, 6-hydroxyhexanoate, and adipate. Cell extracts obtained from this strain grown on CHAM contained CHAM oxidase, and the model for CHAM oxidation by this enzyme was similar to the model for deamino oxidation of amine by amine oxidase.


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Related Concepts

Microbacterium oxydans
Pyruvate Dehydrogenase E3-Binding Protein Deficiency
Cyclohexylamine oxidase
Oxidoreductases Acting on CH-NH Group Donors
Amine oxidase
Monoamine Oxidase

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