Biodegradation of polyhydroxyalkanoic acids

Applied Microbiology and Biotechnology
D JendrossekH G Schlegel

Abstract

Stimulated by the commercial availability of bacteriologically produced polyesters such as poly[(R)-3-hydroxybutyric acid], and encouraged by the discovery of new constituents of polyhydroxyalkanoic acids (PHA), a considerable body of knowledge on the metabolism of PHA in microorganisms has accumulated. The objective of this essay is to give an overview on the biodegradation of PHA. The following topics are discussed: (i) general considerations of PHA degradation, (ii) methods for identification and isolation of PHA-degrading microorganisms, (iii) characterization of PHA-degrading microorganisms, (iv) biochemical properties of PHA depolymerases, (v) mechanisms of PHA hydrolysis, (vi) regulation of PHA depolymerase synthesis, (vii) molecular biology of PHA depolymerases, (viii) influence of the physicochemical properties of PHA on its biodegradability, (ix) degradation of polyesters related to PHA, (x) biotechnological aspects of PHA and PHA depolymerases.

Citations

May 15, 2003·Folia Microbiologica·M FliegerJ Votruba
Sep 22, 2005·Applied Microbiology and Biotechnology·Soazig C DelamarreCarl A Batt
Sep 15, 2005·Applied Microbiology and Biotechnology·Gloria Soberón-ChávezEric Déziel
May 5, 2006·Applied Microbiology and Biotechnology·Zhong ZhengGuo-Qiang Chen
Feb 24, 2007·Applied Microbiology and Biotechnology·Dieter Jendrossek
Feb 14, 2009·Applied Microbiology and Biotechnology·Christos P PapaneophytouDimitrios A Kyriakidis
Nov 11, 2003·International Journal of Biological Macromolecules·Ken-ichi KasuyaYoshiharu Doi
Apr 2, 2002·Chemosphere·Merja ItävaaraJohan-Fredrik Selin
May 20, 1998·International Journal of Biological Macromolecules·M ShinomiyaY Doi
Jul 23, 1999·International Journal of Biological Macromolecules·B H Rehm, A Steinbüchel
Jul 23, 1999·International Journal of Biological Macromolecules·R QuinterosW H Park
Jul 23, 1999·International Journal of Biological Macromolecules·H Abe, Y Doi
Jul 17, 1999·International Journal of Biological Macromolecules·K KasuyaY Doi
Nov 10, 1998·Trends in Biotechnology·A Steinbüchel, B Füchtenbusch
Mar 14, 2001·Journal of Biotechnology·D M Abou-ZeidW D Deckwer
Jun 19, 2001·Current Opinion in Biotechnology·M Shimao
Apr 21, 1999·Current Opinion in Biotechnology·Y Poirier
Oct 20, 2005·Journal of Bioscience and Bioengineering·Teruyuki Kobayashi, Terumi Saito
Jun 3, 2010·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Sachin WakadkarAnastassios C Papageorgiou
Jun 15, 2010·Applied and Environmental Microbiology·Björn Andreessen, Alexander Steinbüchel
Dec 25, 2007·Applied and Environmental Microbiology·Keiichi UchinoDieter Jendrossek
Jul 9, 2004·Applied and Environmental Microbiology·Zhong ZhengGuo-Qiang Chen
Oct 22, 2013·Journal of Biological Engineering·Asif RahmanCharles D Miller
Oct 20, 2005·Journal of Bioscience and Bioengineering·Hiromi UchidaToshiaki Nakajima-Kambe

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.