Biodiversity and hypervirulence of Listeria monocytogenes

Nature Genetics
Yonatan H Grad, Sarah M Fortune

Abstract

The integration of large, well-sampled collections of bacterial isolates with genomics and experimental methods provides opportunities for 'top-down' discovery of the genetic basis of phenotypes of interest. In a new report, the authors apply this approach to investigate the heterogeneity in manifestations of disease caused by Listeria monocytogenes and demonstrate that a previously uncharacterized cellobiose PTS system is involved in central nervous system infection.

References

Jul 4, 2001·Clinical Microbiology Reviews·J A Vázquez-BolandJ Kreft
Jan 5, 2011·Emerging Infectious Diseases·Elaine ScallanPatricia M Griffin
Feb 20, 2014·Frontiers in Cellular and Infection Microbiology·Cormac G M Gahan, Colin Hill
Feb 2, 2016·Nature Genetics·Mylène M MauryMarc Lecuit

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