PMID: 6971030Jan 1, 1980Paper

Bioelectric correlates of the brain's protective mechanisms

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
N P Bekhtereva

Abstract

The author substantiates the necessity of searching for new means producing a therapeutic effect on the brain of epileptic patients that would be similar, in principle, to the brain's own protective mechanisms. This can be done, in the author's opinion, on the basis of studying the most probable bioelectric equivalents of the protective mechanisms. The author suggests a new method for suppressing the epileptogenic focus. This suppression, close to the physiological one, is effected by applying a weak sinusoidal current to the focus via intracerebrally implanted electrodes. Data on the suppression of the epileptiform activity within the zone of the current application, as well as data confirming the local character of the current action are presented. The place of the new method in the system of complex therapy, particularly of epilepsy, is determined with consideration of the role of the stable pathological state. Probable neurophysiological mechanisms of the sinusoidal current action on the epileptogenic focus are discussed.

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Related Papers

Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
A G Zemskaia, N P Riabukha
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
A B Sitel'
© 2021 Meta ULC. All rights reserved