Bioelectromagnetic forward problem: isolated source approach revis(it)ed

Physics in Medicine and Biology
M Stenroos, J Sarvas

Abstract

Electro- and magnetoencephalography (EEG and MEG) are non-invasive modalities for studying the electrical activity of the brain by measuring voltages on the scalp and magnetic fields outside the head. In the forward problem of EEG and MEG, the relationship between the neural sources and resulting signals is characterized using electromagnetic field theory. This forward problem is commonly solved with the boundary-element method (BEM). The EEG forward problem is numerically challenging due to the low relative conductivity of the skull. In this work, we revise the isolated source approach (ISA) that enables the accurate, computationally efficient BEM solution of this problem. The ISA is formulated for generic basis and weight functions that enable the use of Galerkin weighting. The implementation of the ISA-formulated linear Galerkin BEM (LGISA) is first verified in spherical geometry. Then, the LGISA is compared with conventional Galerkin and symmetric BEM approaches in a realistic 3-shell EEG/MEG model. The results show that the LGISA is a state-of-the-art method for EEG/MEG forward modeling: the ISA formulation increases the accuracy and decreases the computational load. Contrary to some earlier studies, the results show that ...Continue Reading

References

Oct 1, 1989·IEEE Transactions on Bio-medical Engineering·J W MeijsA van Oosterom
Feb 1, 1989·IEEE Transactions on Bio-medical Engineering·M S Hämäläinen, J Sarvas
May 1, 1994·IEEE Transactions on Bio-medical Engineering·A S FergusonG Stroink
Mar 1, 1997·IEEE Transactions on Bio-medical Engineering·S B BaumannF M Meno
Mar 31, 1999·IEEE Transactions on Bio-medical Engineering·J C MosherP S Lewis
Mar 6, 2002·IEEE Transactions on Bio-medical Engineering·Gerald FischerPaul Wach
Aug 28, 2003·Computer Methods and Programs in Biomedicine·Jyrki Lötjönen
Oct 16, 2004·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Juha Koikkalainen, Jyrki Lötjönen
Jan 11, 2005·IEEE Transactions on Medical Imaging·Jan KybicThéo Papadopoulo
Jun 24, 2005·Physics in Medicine and Biology·Nevzat G Gençer, Zeynep Akalin-Acar
Sep 24, 2005·Physics in Medicine and Biology·Jan KybicThéo Papadopoulo
Nov 21, 2007·Computer Methods and Programs in Biomedicine·M StenroosJ Nenonen
May 12, 2010·Journal of Neuroscience Methods·Zeynep Akalin Acar, Scott Makeig
Aug 7, 2010·Human Brain Mapping·Moritz DannhauerThomas R Knösche
Mar 26, 2011·Computational Intelligence and Neuroscience·Alexandre GramfortMaureen Clerc

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Citations

Mar 4, 2014·NeuroImage·Gregor StrobbeStefaan Vandenberghe
Sep 5, 2013·Brain Topography·Victoria Montes-RestrepoHans Hallez
Jun 9, 2015·IEEE Transactions on Bio-medical Engineering·Martin BauerCarsten H Wolters
Jul 31, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Aapo NummenmaaTommi Raij
Oct 29, 2013·NeuroImage·Alexandre GramfortMatti S Hämäläinen
Jun 14, 2016·NeuroImage·Tuomas P MutanenRisto J Ilmoniemi
Mar 28, 2018·Biomedical Engineering Online·Johannes VorwerkCarsten H Wolters
Nov 16, 2016·Physics in Medicine and Biology·S PursiainenC H Wolters
Aug 29, 2018·Brain Connectivity·Karita Suvi-Tuuli SaloRisto J Ilmoniemi
Dec 24, 2018·Physics in Medicine and Biology·Axelle PillainFrancesco Andriulli
Nov 18, 2016·Journal of Neurophysiology·S PursiainenC H Wolters
Jul 11, 2019·Brain Topography·Karita S-T SaloRisto J Ilmoniemi
Feb 20, 2018·Frontiers in Neuroscience·Maria Carla PiastraCarsten H Wolters
Oct 21, 2018·Brain Topography·Ernesto Cuartas MoralesDante Mantini
Jun 24, 2018·Brain Topography·Rasmus ZetterLauri Parkkonen
Dec 12, 2020·Scientific Reports·Tim M TierneyGareth R Barnes
Apr 17, 2020·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kyohei SakakiAtsushi Okawa
Jun 5, 2021·PloS One·Sophie SchraderChristian Engwer
Jul 9, 2021·Frontiers in Human Neuroscience·Pedro Caldana GordonChristoph Zrenner

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