Bioengineering approaches to controlled protein delivery

Pediatric Research
Serge Kobsa, W Mark Saltzman

Abstract

Proteins are of crucial importance in all biologic organisms, in terms of both structure and function. Their deficits play central roles in many pathologic states, and their potential as powerful therapeutic agents has been widely recognized. Many issues, however, exist in delivery of biologically active proteins to target tissues and organs. Recent advances in biomedical engineering have lead to development of advanced techniques for controlled delivery of peptides and proteins, paving the way for their efficient use in treating human injury and disease. With a particular emphasis on most recent advances, this review discusses currently available techniques for controlled delivery of proteins and considers future research directions.

References

Nov 1, 1979·Annals of Internal Medicine·D D Von HoffF M Muggia
Oct 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·W A FrazierR A Bradshaw
Oct 1, 1994·Journal of Cellular Biochemistry·L G Cima
Oct 1, 1996·Journal of Biomedical Materials Research·L J Mikulec, D A Puleo
Jan 1, 1996·Journal of Biomaterials Science. Polymer Edition·C E KrewsonW M Saltzman
Jul 2, 1998·Journal of Biomaterials Science. Polymer Edition·K ShakesheffR Langer
Nov 5, 1998·Journal of Controlled Release : Official Journal of the Controlled Release Society·M MorlockG Winter
Dec 22, 1998·Journal of Biomaterials Science. Polymer Edition·M C PetersD J Mooney
Mar 1, 2000·Proceedings of the National Academy of Sciences of the United States of America·V P ShastriR Langer
Mar 4, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·G P CarinoE Mathiowitz
Mar 4, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·H MaedaK Hori
Jun 6, 2000·Advanced Drug Delivery Reviews· Mark Saltzman W, S P Baldwin
Feb 13, 2001·Journal of Controlled Release : Official Journal of the Controlled Release Society·K S SoppimathW E Rudzinski
Jun 8, 2001·Journal of Controlled Release : Official Journal of the Controlled Release Society·J L ClelandA Cuthbertson
Jun 28, 2001·Journal of Biomedical Materials Research·R BiranP A Tresco
Aug 8, 2001·Journal of Controlled Release : Official Journal of the Controlled Release Society·K HanJ S Park
Nov 2, 2001·Nature Biotechnology·T P RichardsonD J Mooney
Nov 17, 2001·Chemical Reviews·K Y Lee, D J Mooney
Nov 22, 2001·American Journal of Obstetrics and Gynecology·S K HunterA M Krieg
Dec 6, 2001·Journal of Controlled Release : Official Journal of the Controlled Release Society·I GentaB Conti
Feb 28, 2002·Biomacromolecules·Jörg K TessmarAchim Göpferich
May 23, 2002·Journal of Biomaterials Science. Polymer Edition·Thomas M MeeseKacey G Marra
Jul 18, 2002·Nature Reviews. Drug Discovery·W Mark Saltzman, William L Olbricht
Oct 3, 2002·The Journal of Pharmacy and Pharmacology·Shaobing ZhouJihui Ma
Oct 24, 2002·Advanced Drug Delivery Reviews·S Sershen, J West
Dec 7, 2002·Journal of Controlled Release : Official Journal of the Controlled Release Society·Elizabeth L HedbergAntonios G Mikos
Mar 6, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·J SohierJ M Bezemer
Mar 12, 2003·Advanced Drug Delivery Reviews·Jayanth Panyam, Vinod Labhasetwar
Mar 12, 2003·Advanced Drug Delivery Reviews·Hidenori OtsukaKazunori Kataoka
Jul 26, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·V R Sinha, Aman Trehan
Nov 6, 2003·International Journal of Biological Macromolecules·X H WangX H Song
Mar 20, 2004·Science·Theresa M Allen, Pieter R Cullis
Sep 1, 2004·International Journal of Pharmaceutics·S Freiberg, X X Zhu
Jun 11, 2005·Pharmaceutical Research·Vera LuginbuehlLorenz Meinel

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Citations

Feb 20, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sara Royce Hynes, Erin B Lavik
Feb 6, 2010·Journal of the American Chemical Society·Partha GhoshVincent M Rotello
Mar 25, 2008·Pediatric Research·James C Y Dunn
Apr 17, 2012·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Piyush Koria
May 27, 2014·Biotechnology Advances·Lara Yildirimer, Alexander M Seifalian
Sep 8, 2015·International Journal of Molecular Sciences·Piergiorgio GentileZebunnissa Ramtoola
Jan 30, 2016·Trends in Biotechnology·Youhui LinXiang Yang Liu
Mar 17, 2012·Journal of Controlled Release : Official Journal of the Controlled Release Society·Roberta CensiWim E Hennink
Jul 26, 2011·Journal of the Mechanical Behavior of Biomedical Materials·Vijay Kumar NandagiriGianluca Ciardelli
May 25, 2010·Biomaterials·Fa-Ming ChenZhi-Fen Wu
Nov 13, 2008·Current Opinion in Biotechnology·Pamela HamillRobert E W Hancock
Mar 6, 2015·Frontiers in Cellular Neuroscience·Oscar A Carballo-Molina, Iván Velasco
Aug 11, 2016·Scientific Reports·Chaitanya Kumar ThotaVirander Singh Chauhan
Sep 7, 2016·Tissue Engineering. Part B, Reviews·Grace WaldenAram Saeed
Mar 16, 2017·Pharmaceutical Development and Technology·Manish GuptaNashiru Billa
Sep 2, 2020·Advanced Drug Delivery Reviews·Anastasia VarankoAshutosh Chilkoti
May 14, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Inchirah AdalaFelicity R A J Rose

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