Biofabricated constructs as tissue models: a short review

Journal of Materials Science. Materials in Medicine
Pedro F Costa

Abstract

Biofabrication is currently able to provide reliable models for studying the development of cells and tissues into multiple environments. As the complexity of biofabricated constructs is becoming increasingly higher their ability to closely mimic native tissues and organs is also increasing. Various biofabrication technologies currently allow to precisely build cell/tissue constructs at multiple dimension ranges with great accuracy. Such technologies are also able to assemble together multiple types of cells and/or materials and generate constructs closely mimicking various types of tissues. Furthermore, the high degree of automation involved in these technologies enables the study of large arrays of testing conditions within increasingly smaller and automated devices both in vitro and in vivo. Despite not yet being able to generate constructs similar to complex tissues and organs, biofabrication is rapidly evolving in that direction. One major hurdle to be overcome in order for such level of complex detail to be achieved is the ability to generate complex vascular structures within biofabricated constructs. This review describes several of the most relevant technologies and methodologies currently utilized within biofabricatio...Continue Reading

References

Oct 1, 1975·The Journal of Experimental Zoology·K Schmidt-Nielsen
May 14, 1993·Science·R Langer, J P Vacanti
Jan 7, 1998·Clinical Therapeutics·W H Eaglstein, V Falanga
Nov 5, 1999·Nature Biotechnology·A Y FuS R Quake
Feb 24, 2001·The New England Journal of Medicine·R QuartoM Marcacci
Nov 27, 2001·Science·E CukiermanK M Yamada
Jun 15, 2004·Nature Biotechnology·Daniel G AndersonRobert Langer
Nov 2, 2004·Nature Materials·Joachim Kohn
Dec 24, 2004·Lab on a Chip·Dirk R AlbrechtSangeeta N Bhatia
Mar 18, 2005·Annals of Biomedical Engineering·Jason A BarronBradley R Ringeisen
Jul 9, 2005·Nature Materials·Scott J Hollister
Aug 2, 2005·Seminars in Cancer Biology·Anna BirgersdotterIngemar Ernberg
Oct 20, 2005·Journal of Bioscience and Bioengineering·Hiroshi KurosawaYoshifumi Amano
Aug 31, 2006·Biotechnology Journal·Paul D DaltonMartin Möller
Feb 6, 2007·Journal of Biotechnology·Vera MeyerArthur F J Ram
Jul 3, 2007·British Journal of Pharmacology·D A Pereira, J A Williams
Aug 4, 2007·The Review of Scientific Instruments·Carl G SimonMatthew L Becker
Jul 21, 2009·Acta Biomaterialia·Szilvia EosolyLisa Looney
Aug 12, 2009·Biomaterials·Cyrille NorotteGabor Forgacs
Jan 23, 2010·Nature Materials·Dietmar W Hutmacher
Jun 1, 2009·Biofabrication·V MironovR Markwald
Jun 10, 2011·Lab on a Chip·Azmi YusofPeter Koltay
Nov 19, 2011·Advanced Materials·Toby D BrownDietmar W Hutmacher
Feb 22, 2012·Environmental Science & Technology·Clément LevardGordon E Brown
Mar 24, 2012·Lab on a Chip·Loes I SegerinkAlbert van den Berg
Jun 7, 2012·Journal of Periodontology·Darnell KaiglerDavid J Mooney
May 9, 2013·Integrative Biology : Quantitative Biosciences From Nano to Macro·Gustavo A HigueraLorenzo Moroni
Dec 7, 2013·Journal of Clinical Periodontology·Pedro F CostaDietmar W Hutmacher
Feb 20, 2014·Advanced Materials·David B KoleskyJennifer A Lewis
Jun 7, 2014·Annual Review of Biomedical Engineering·Piyush BajajRashid Bashir

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Citations

Nov 2, 2015·International Journal of Pharmaceutics·Pedro F CostaCarmen Alvarez-Lorenzo

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