Biofilm formation by vaginal Lactobacillus in vivo

Medical Hypotheses
Gary VentoliniM Salazar

Abstract

Biofilm formation by nonpathogenic bacteria is responsible for their stable maintenance in vivo ecosystems as it promotes long-term permanence on the host's vaginal mucosa. Biofilm formation by Lactobacilli has been reported in vitro but not in vivo. We hypothesize the presence of biofilm formation in vivo could be also documented by microscope photographs (MP) of wet mounts obtained from uninfected vaginal samples satisfying rigorous scientific identification criteria. We analyzed 400 MP from our database, and we were able to determine that 12 MP from 6 different patients contained clues of the formation of biofilm by Lactobacilli. The most probable lactobacillus involved is presumed to be Lactobacillus jensenii. The documentation of biofilm formation by vaginal Lactobacilli at fresh wet mount preparation is significant and has several important clinical preventive and therapeutic implications.

References

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Citations

Nov 26, 2015·Future Microbiology·Rebecca A Gabrilska, Kendra P Rumbaugh
May 6, 2016·Archives of Microbiology·María Cecilia Leccese TerrafMaría Elena Fátima Nader-Macías
May 27, 2016·Scientific Reports·Natalia Schlabritz-LoutsevitchGary Ventolini
Mar 31, 2017·Critical Reviews in Microbiology·Hyun-Sul JungMarleen M Kock
Feb 12, 2021·Frontiers in Cellular and Infection Microbiology·Fenghao ZhangTingtao Chen

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