Biofilm-grown Mycoplasma mycoides subsp. mycoides SC exhibit both phenotypic and genotypic variation compared with planktonic cells

Veterinary Microbiology
Laura McAuliffeRobin A J Nicholas

Abstract

Biofilm formation where bacterial cells adhere to a surface and surround themselves in a polysaccharide matrix is thought to be an important factor in disease initiation and persistence for many bacterial species. We have examined biofilm formation by Mycoplasma mycoides subsp. mycoides small colony using a simple model without an air/liquid interface and have found that adherent Mmm SC was more resistant to many stresses, including heat, osmotic shock and oxidative stress. Biofilms of Mmm SC also exhibited remarkable persistence and were able to survive for up to 20 weeks in stationary phase. Significant variation was seen between Mmm SC strains in their ability to form a biofilm and the morphology of the biofilm produced with some strains unable to produce microcolonies. Proteomic analysis found that a number of proteins linked to adherence were over-expressed in biofilms compared with planktonic cells.

References

Apr 1, 1991·Journal of Medical Microbiology·R J MilesH Varsani
Jun 1, 1997·Microbiology·G Ben-MenachemS Rottem
May 21, 1999·Science·J W CostertonE P Greenberg
Feb 13, 2001·Trends in Microbiology·T F Mah, G A O'Toole
Sep 7, 2001·Journal of Bacteriology·S DhandayuthapaniJ B Baseman
Jun 9, 2004·Applied and Environmental Microbiology·J WelinG Svensäter
Sep 29, 2005·Antimicrobial Agents and Chemotherapy·Lina Fassi FehriAlain Blanchard
Dec 5, 2006·Journal of Bacteriology·Warren L SimmonsKevin Dybvig

❮ Previous
Next ❯

Citations

Oct 26, 2010·Animal Health Research Reviews·Mario JacquesYannick D N Tremblay
Jul 31, 2012·Veterinary Microbiology·Hongjun ChenChan Ding
Jan 16, 2014·Journal of Neuropathology and Experimental Neurology·Frank O Bastian
Sep 12, 2017·The Journal of Veterinary Medical Science·Dereje Damte TassewSeung-Chun Park
Jun 11, 2010·Clinical and Vaccine Immunology : CVI·Philippe TottéLaurence Dedieu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.