Biofilm in wound care

British Journal of Community Nursing
Kumal Rajpaul

Abstract

A biofilm can be described as a microbial colony encased in a polysaccharide matrix which can become attached to a wound surface. This can affect the healing potential of chronic wounds due to the production of destructive enzymes and toxins which can promote a chronic inflammatory state within the wound. Biofilms can be polymicrobial and can result in delayed wound healing and chronic wound infection resistant to antibiotics, leading to prolonged hospitalisation for some patients. There appears to be a correlation between biofilms and non-healing in chronic wounds. It is suggested that biofilms are a major player in the chronicity of wounds. They are a complex concept to diagnose and management needs to be multifactorial.

References

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Citations

Jan 8, 2016·Experimental Dermatology·Maria Luisa MangoniMichael Zasloff
Jun 11, 2016·International Wound Journal·Silvestre Ortega-PeñaEdgar Krötzsch
Jun 28, 2016·British Journal of Nursing : BJN·Nina Murphy
Sep 7, 2016·British Journal of Community Nursing·Jennifer Hurlow
Jun 26, 2015·British Journal of Nursing : BJN·Edwin Tapiwa ChamangaJohanna M Jandrisits
Apr 11, 2018·Cell and Tissue Research·Ruijie ZengHaihong Li
Jun 27, 2019·British Journal of Nursing : BJN·Jeanette Milne
Jul 14, 2020·Journal of Wound Care·Randall D WolcottMichel He Hermans

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