Biofilms on right heart flow-directed catheters
This study was designed to detect biofilm and bacteria on right heart flow-directed catheters using scanning electron microscopy and culture following scraping and dispersion of biofilm by sonication. We examined 20 consecutive catheters removed from 18 critically ill patients, an average of 2.6 days after insertion. On scanning electron microscopy, all catheters were found to be covered by a biofilm, with bacteria visible on 50 percent of them. Cultures of specimens from 40 percent of the catheters grew skin organisms (Staphylococcus warneri, Diphtheroid), anaerobes (Propionibacterium), and other potential pathogens (Proteus vulgaris, Enterobacter cloacae). Combination of the two techniques produced a bacterial detection rate of 75 percent. This study demonstrates that the presence of biofilm with bacterial adherence is common on right heart flow-directed catheters. The phenomenon could play a significant role in endogenous infection in critically ill patients.
Rapid diagnosis of intravascular catheter-associated infection by direct Gram staining of catheter segments
Study of the incidence of intravascular catheter infection and associated septicemia in critically ill patients
Right-sided infective endocarditis as a consequence of flow-directed pulmonary-artery catheterization. A clinicopathological study of 55 autopsied patients
A scanning and transmission electron microscopic study of the surfaces of intrauterine contraceptive devices
Impact of using an indwelling introducer on diagnosis of Swan-Ganz pulmonary artery catheter colonization
Staphylococcus warneri ventriculoperitoneal shunt infection: failure of diagnosis by ventricular CSF sampling
Electron microscopic studies of endotracheal tubes used in neonates: do microbes adhere to the polymer?
Staphylococcus warneri endocarditis after implantation of a lumbar disc prosthesis in an immunocompetent patient
Electron-microscopic description of accretions occurring on tips of infected and non-infected central venous catheters
Role of topical phospholipids in the prophylaxis of silicone elastomer-associated infection in the abdominal cavity
Infection of pulmonary artery catheters. Epidemiologic characteristics and multivariate analysis of risk factors
Chronic prosthetic valve endocarditis due to Propionibacterium acnes: an unexpected cause of prosthetic valve dysfunction
The pathogenesis and epidemiology of catheter-related infection with pulmonary artery Swan-Ganz catheters: a prospective study utilizing molecular subtyping
Is biofilm accumulation on endoscope tubing a contributor to the failure of cleaning and decontamination?
Device-related infections in critically ill patients. Part II: Prevention of ventilator-associated pneumonia and urinary tract infections
Mechanisms and risk factors for infection of pulmonary artery catheters and introducer sheaths in cancer patients admitted to an intensive care unit
Propionibacterium acnes Recovered from Atherosclerotic Human Carotid Arteries Undergoes Biofilm Dispersion and Releases Lipolytic and Proteolytic Enzymes in Response to Norepinephrine Challenge In Vitro
Biofilm & Infectious Disease
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.