Biofunctional properties of caseinophosphopeptides in the oral cavity

Caries Research
A B Nongonierma, R J FitzGerald

Abstract

Caseinophosphopeptides (CPPs), bioactive peptides released from caseins, have the ability to enhance bivalent mineral solubility. This is relevant to numerous biological functions in the oral cavity (promotion of tooth enamel remineralisation, prevention of demineralisation and buffering of plaque pH). Therefore, CPPs may play a positive role as prophylactic agents for caries, enamel erosion and regression of white spot lesions. Most in vitro and in situ studies demonstrate strong evidence for the bioactivity of CPPs in the oral cavity. Nevertheless, relatively little is known concerning their use as adjuvants for oral health and more particularly regarding their long-term effects on oral health.

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Citations

Sep 21, 2013·Journal of Agricultural and Food Chemistry·Celia Conesa, Richard J FitzGerald
Sep 3, 2013·Journal of Agricultural and Food Chemistry·Florian BaumMonika Pischetsrieder
Aug 25, 2015·Peptides·Alice B Nongonierma, Richard J FitzGerald
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Jan 18, 2019·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Maryam DoozandehMohammad Hossein Dashti
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Dec 21, 2017·Analytical and Bioanalytical Chemistry·Alice B Nongonierma, Richard J FitzGerald
Jan 20, 2021·Nutrition Research Reviews·Alba Miguéns-GómezMontserrat Pinent
Apr 23, 2021·Dental Materials Journal·Keiki NakamuraTakashi Muramatsu
Aug 16, 2021·International Journal of Dental Hygiene·Patrícia Regina Almeida de OliveiraMônica Almeida Tostes

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