PMID: 2489054Feb 1, 1989Paper

Biological activities of synthetic polypeptides containing a repetitive core sequence (Arg-Gly-Asp) of cell adhesion molecules

International Journal of Biological Macromolecules
I SaikiK Matsuno

Abstract

A unique polypeptide containing the repeated structure of core sequence from cell adhesion molecules, poly(Arg-Gly-Asp), was successfully prepared by the polymerization procedure with diphenylphosphoryl azide. This polypeptide dramatically inhibited the aggregation of platelets induced by adenosine diphosphate (ADP) or malignant melanoma cells.

References

Oct 23, 1987·Science·E Ruoslahti, M D Pierschbacher
May 1, 1973·International Journal of Cancer. Journal International Du Cancer·G J GasicS Murphy
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M D Pierschbacher, E Ruoslahti

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Citations

Jun 2, 2006·Toxicon : Official Journal of the International Society on Toxinology·Katia Sabrina PaludoCélia Regina Cavichiolo Franco
Jan 1, 1993·Journal of Biomaterials Science. Polymer Edition·Y HiranoA Nakajima
Mar 1, 1994·Medicinal Research Reviews·D CoxK Yoshida
Sep 1, 1991·International Journal of Peptide and Protein Research·J MurataI Azuma
Aug 1, 1989·International Journal of Biological Macromolecules·J MurataS Tokura
Nov 1, 1991·Journal of Biomedical Materials Research·Y ItoY Imanishi
Jan 20, 1998·Japanese Journal of Pharmacology·I Saiki

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Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

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