PMID: 16523720Mar 10, 2006Paper

Biological activity and pharmacological prospects of lupane terpenoids: I. Natural lupane derivatives

Bioorganicheskaia khimiia
T G TolstikovaO B Flekhter

Abstract

The biological activity of natural and semisynthetic lupane triterpenoids is discussed in a two-part review. The first part is devoted to the pharmacological properties of natural lupane triterpenoids. Betulinic acid has proven to be the most effective antitumor agent among more than fifty natural lupanes.

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