PMID: 9178568May 1, 1997Paper

Biological activity of purpurogallin

Bioscience, Biotechnology, and Biochemistry
Yoshihiko InamoriHiroshi Tsujibo

Abstract

Purpurogallin showed antibacterial activity toward gram-positive bacteria. Strong activity against methicillin-resistant Staphylococcus aureus [minimal inhibitory concentration (MIC) against methicillin of 1600 micrograms/ml] was found, with MIC of 11.0 micrograms/ml. Purpurogallin inhibited the growth of all tested plants and decreased the chlorophyll content in the cotyledons of Brassica campestris subsp. rapa. It showed potent inhibitory activity against prolyl endopeptidase (the 50% inhibitory concentration was 1.6 x 10(-5) M), unlike its analogues, hinokitiol and tropolone.

Citations

May 27, 2005·Antimicrobial Agents and Chemotherapy·Hiroaki YamanoToshio Kishimoto
Aug 1, 2014·Journal of Environmental Sciences (China)·Junyi HuYingqian Xu
Nov 28, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Christina N KontoghiorgheGeorge J Kontoghiorghes
Jul 31, 2010·Nature Reviews. Drug Discovery·Klaus Strebhardt
Nov 27, 2008·The Journal of Biological Chemistry·Nobumoto WatanabeHiroyuki Osada

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