Biological apatite vs hydroxyapatite at the atomic level.

Clinical Orthopaedics and Related Research
R A Young

Abstract

Known differences in chemical content of biological apatites, specifically the dense (sp.g. greater than 2.95) portion of human tooth enamel (TE), and of stoichiometric hydroxyapatite (OHAp) imply atomic-scale crystal-structural differences, via major and minor substitutions, which can impart very different characteristics to the two materials. Further, some substitutions are shown to produce important effects not predictable from study of pure materials alone. A number of crystal-detail differences between TE and OHAp, both at room temperature and in response to heating (which occurs to some degree locally in hard tissue in vivo as a result of grinding, laser action, etc.), are tabulated. They include CO3 content and incorporation, lattice parameters, water content, non OHAp phases formed on heating, structural OH deficiency, and hydrogen-bonding of F and Cl "impurities" to OH. The significance of these differences is such that it is clearly misleading to speak of tooth enamel, and by inference other biological apatites, as "hydroxyapatite" without considerable qualification of the statement. The differences between biological apatite and OHAp are, in fact, of greater current interest and probable biological significance than ...Continue Reading

Citations

Aug 1, 1991·Calcified Tissue International·M IijimaY Moriwaki
Jun 1, 1989·The Anatomical Record·P V Hauschka, F H Wians
Feb 1, 1988·Journal of Electron Microscopy Technique·M D McKeeH Warshawsky
Jan 1, 1984·Archives of Orthopaedic and Trauma Surgery·B D Katthagen, H Mittelmeier
Jan 1, 1995·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J P Simmer, A G Fincham
Jan 2, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C RobinsonJ Kirkham
Jun 15, 2007·Journal of Materials Science. Materials in Medicine·Myung Chul Chang, William H Douglas
Jan 1, 1981·Calcified Tissue International·R M VerbeeckJ W Vrolijk
Apr 1, 1996·European Journal of Oral Sciences·D T Zero
Feb 11, 2011·Journal of Forensic Sciences·Sophie BeckettJohn G Clement
Aug 8, 2015·Physical Chemistry Chemical Physics : PCCP·Sergio E Ruiz HernandezNora H de Leeuw
Mar 1, 1979·Journal of Dental Research·E D Eanes
Oct 1, 1981·Journal of Dental Research·A F Marshall, K R Lawless
Mar 1, 1986·Journal of Dental Research·F F de MulJ J ten Bosch
Mar 12, 2008·Journal of Materials Science. Materials in Medicine·Myung Chul Chang
May 5, 2017·Physiological Reviews·Rodrigo S LacruzMichael L Paine
Dec 8, 1978·Calcified Tissue Research·R Z LeGerosR Legros
Apr 18, 2006·Journal of Materials Science. Materials in Medicine·Myung Chul ChangJunzo Tanaka
Jul 19, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Stefanie ShielsJoo L Ong
Jul 30, 2016·Progress in Biomaterials·Sergey V Dorozhkin
Nov 26, 1979·Calcified Tissue International·H J HeijligersR M Verbeeck
Feb 5, 2009·Journal of Biomaterials Science. Polymer Edition·Myung Chul ChangWilliam H Douglas
Jul 28, 2020·Acta Biomaterialia·Cayla A StiflerPupa U P A Gilbert
Dec 9, 1992·Clinical Materials·R Z LeGeros
Sep 24, 2009·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·C Robinson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.