PMID: 9557734Apr 29, 1998Paper

Biological characterization of Rev variation in equine infectious anemia virus

Journal of Virology
M BelshanSusan Carpenter

Abstract

Sequence analysis identified significant variation in the second exon of equine infectious anemia virus (EIAV) rev. Functional analysis indicated that limited amino acid variation in Rev significantly altered the export activity of the protein but did not affect Rev-dependent alternative splicing. EIAV Rev can mediate export through two independent cis-acting Rev-responsive elements (RREs), and differences among Rev variants were more pronounced when both RREs were present. Variation in Rev may be an important mechanism for regulation of virus replication in vivo and may contribute to changes in clinical disease.

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Citations

Oct 29, 2003·Journal of Virology·Prasith BaccamSusan Carpenter
Mar 27, 2009·The Journal of General Virology·H C T GroomA M L Lever
Jul 28, 2009·The Journal of Biological Chemistry·Jennifer A MertzJaquelin P Dudley
Jun 30, 2005·Animal Health Research Reviews·Marie-Claude St-LouisDenis Archambault
Jul 25, 2000·Journal of Virology·R J MillerN Sarver
Oct 9, 2002·Medicinal Research Reviews·Elena A LesnikDavid J Ecker
Apr 18, 2000·The Journal of General Virology·R Rosin-ArbesfeldA Gazit
Mar 17, 2017·Transboundary and Emerging Diseases·K CappelliS Capomaccio

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