Biological component of the NIMH clinical research branch collaborative program on the psychobiology of depression: II. Methodology and data analysis

Psychological Medicine
S SecundaR Casper

Abstract

A preceding paper has reviewed the history, background, and rationale for this collaborative effort exploring the biologic basis of the affective disorders. This paper details the "flow" of a subject through the experimental protocol, the instrumentation used to obtain the clinical and behavioural data, and the biologic methodologies employed in the analysis of the body fluids. Data management and analysis techniques developed for this study are also examined.

References

Jan 1, 1977·Annual Review of Pharmacology and Toxicology·J W Maas
Jan 1, 1977·Psychoneuroendocrinology·R C CasperH Dekirmenjian
Jul 1, 1979·Archives of General Psychiatry·M M KatzS H Koslow
Feb 1, 1975·The Journal of Clinical Endocrinology and Metabolism·A Liotta, D T Krieger
Sep 1, 1975·Archives of General Psychiatry·R J Baldessarini
Jul 1, 1977·Clinical Pharmacokinetics·L F Gram
Apr 1, 1977·Alcoholism, Clinical and Experimental Research·S E Gitlow
Jun 1, 1978·Archives of General Psychiatry·R L SpitzerE Robins
Jul 1, 1978·Archives of General Psychiatry·J Endicott, R L Spitzer
Aug 1, 1978·The Journal of Surgical Research·R E Kuttner, J J Spitzer
Feb 1, 1977·The American Journal of Psychiatry·J B Brown
Oct 1, 1977·Canadian Psychiatric Association Journal·F W FurlongB M Kapur
Jan 1, 1976·Acta Pharmacologica Et Toxicologica·D Fremstad, K Bergerud
Jan 1, 1975·Archives of General Psychiatry·P H GruenJ Sassin
Feb 20, 1975·Nature·E G Shaskan, R E Becker
Apr 11, 1975·The American Journal of Psychiatry·W T CarpenterR J Wyatt
Nov 1, 1975·The American Journal of Psychiatry·D L GarverF Deleon-Jones
Nov 1, 1975·The American Journal of Psychiatry·R L SpitzerE Robins
Nov 1, 1975·Clinical Pharmacology and Therapeutics·R H Cotham, D Shand
Feb 1, 1976·Journal of Pharmaceutical Sciences·J T BiggsW R Sherman
Sep 1, 1967·The Journal of Physiology·P J Garrahan, I M Glynn
Jan 1, 1973·Clinical Genetics·K H GustavsonS B Ross
Dec 1, 1968·The Journal of Clinical Investigation·S A Berson, R S Yalow
Sep 1, 1968·The Biochemical Journal·V P Whittaker
Jan 1, 1974·International Pharmacopsychiatry·J RybakowskiK Kasprzak
Jun 1, 1972·JOGN Nursing; Journal of Obstetric, Gynecologic, and Neonatal Nursing·M H Carroll
Mar 1, 1972·Archives of General Psychiatry·J W MaasH Dekirmenjian
Jun 28, 1973·The New England Journal of Medicine·J B Martin
Feb 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·A FrazerJ Mendels

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Citations

Jul 1, 1986·Biological Psychiatry·S K SecundaH Landis
Jul 1, 1994·Journal of Psychiatric Research·J W MaasH Landis
Aug 1, 1993·Journal of Affective Disorders·M M KatzE Robins
May 1, 1986·Psychiatry Research·R D GibbonsP E Stokes
May 1, 1991·Psychiatry Research·A C SwannE Robins
Sep 6, 2012·Journal of the History of the Neurosciences·Shai Mulinari
Oct 20, 2014·Philosophy, Ethics, and Humanities in Medicine : PEHM·Shai Mulinari
May 1, 1983·Journal of Affective Disorders·A FrazerS Secunda
Oct 21, 2003·Statistics in Medicine·Martin M Katz, Nancy Berman
Mar 1, 1987·Acta Psychiatrica Scandinavica·R C CasperD Garver
Jan 16, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ildem DeveciPembegul Gunes
Jan 1, 1986·Annals of the New York Academy of Sciences·J H KocsisB Mason
Jan 1, 1986·The British Journal of Psychiatry : the Journal of Mental Science·J H KocsisD Brunswick
Jan 1, 1986·Annals of the New York Academy of Sciences·S K SecundaJ W Maas

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