Biological degradation of aflatoxin B1 by Rhodococcus erythropolis cultures

International Journal of Food Microbiology
J F AlbertsW H van Zyl

Abstract

Aflatoxin contamination of food and grain poses a serious economic and health problem worldwide, but particularly in Africa. Aflatoxin B(1) (AFB(1)) is extremely mutagenic, toxic and a potent carcinogen to both humans and livestock and chronic exposure to low levels of AFB(1) is a concern. In this study, the biodegradation of aflatoxin B(1) (AFB(1)) by Rhodococcus erythropolis was examined in liquid cultures using thin layer chromatography (TLC), high performance liquid chromatography (HPLC), electro spray mass spectrometry (ESMS) and liquid chromatography mass spectrometry (LCMS). AFB(1) was effectively degraded by extracellular extracts from R. erythropolis liquid cultures. Results indicated that the degradation is enzymatic and that the enzymes responsible for the degradation of AFB(1) are extracellular and constitutively produced. Furthermore, the biodegradation of AFB(1) when treated with R. erythropolis extracellular fraction coincided with a loss of mutagenicity, as evaluated by the Ames test for mutagenicity.

Citations

Jun 8, 2011·Folia Microbiologica·Samuel Edgar TinyiroWeirong Yao
Jul 21, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·G JardA Lebrihi
Dec 15, 2010·International Journal of Molecular Sciences·Shu GuanCheng Ji
Mar 28, 2009·International Journal of Molecular Sciences·Shu GuanTiangui Niu
Jun 21, 2014·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Ramy Sayed Yehia
Mar 7, 2014·International Journal of Molecular Sciences·Jinyou MaLiangbin Hu
Jul 13, 2013·Journal of Chemical Ecology·Susan P McCormick
Feb 20, 2016·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ru JiaLihong Zhao
Oct 25, 2014·Toxins·Lancine SangareYang Liu
Jun 12, 2009·Drug Metabolism Reviews·Qinghua WuKamil Kuca
Aug 30, 2011·Mutation Research·Csilla KrifatonJózsef Kukolya
Sep 9, 2015·Applied Microbiology and Biotechnology·Krisztián LacziGábor Rákhely
Jun 3, 2009·Journal of Applied Microbiology·A Hernandez-MendozaH S Garcia
Mar 19, 2011·Journal of Applied Toxicology : JAT·Ruijie LiuShanshan Wang
Jan 1, 2014·Journal of the Science of Food and Agriculture·Xiaohu LuoZhengxing Chen
May 9, 2015·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Sufang FanYan Zhang
Jan 22, 2015·Transgenic Research·Li-zeng GuanQian-yun Xi
Jul 31, 2013·International Journal of Food Microbiology·M CserhátiJ Kukolya
Dec 24, 2014·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Yuan-Zhen WuDa-Ling Liu
Jul 9, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Rui-yu ZuoQiu-hong Zheng
May 21, 2016·Frontiers in Microbiology·Ilse VanhoutteLeen De Gelder
Jun 14, 2016·International Journal of Food Microbiology·Oluwafemi Ayodeji AdeboVuyo Mavumengwana
Aug 25, 2016·Mycotoxin Research·Petr KarlovskyPierre Dussort
Oct 31, 2015·Critical Reviews in Food Science and Nutrition·O A AdeboV Mavumengwana
Feb 8, 2018·Journal of the Science of Food and Agriculture·Hina ShanakhatSilvana Cavella

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