Biological monitoring of child lead exposure in the Czech Republic

Environmental Health Perspectives
M CikrtE Fitzgerald

Abstract

The area around the Pribram lead smelter has been recognized to be heavily contaminated by lead (Pb). In the early 1970s, several episodes of livestock lead intoxication were reported in this area; thereafter, several epidemiological and ecological studies focused on exposure of children. In contrast to earlier studies, the recent investigation (1992-1994) revealed significantly lower exposure to lead. From 1986-1990, recorded average blood lead levels were about 37.2 micrograms lead (Pb)/100 ml in an elementary school population living in a neighborhood close to the smelter (within 3 km of the plant). The present study, however, has found mean blood lead levels of 11.35 micrograms/100 ml (95% CI = 9.32; 13.82) among a comparable group of children. In addition to blood lead, tooth lead was used to assess exposure among children. Statistically significant differences (p < 0.05) were observed between the geometric mean tooth lead level of 6.44 micrograms Pb/g (n = 13; 95% CI = 3.95; 10.50) in the most contaminated zone and 1.43 micrograms Pb/g (n = 35; 95% CI = 1.11; 1.84) in zones farther away from the point source. Both biomarkers, blood and tooth lead levels, reflect a similar pattern of lead exposure in children. This study h...Continue Reading

References

Feb 1, 1995·Environmental Research·A M BernardR Lauwerys

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Citations

Jun 1, 1997·Environmental Health Perspectives·T J Goehl
Jun 10, 1998·Environmental Health Perspectives·E F FitzgeraldJ E Zejda
Dec 31, 2003·Environmental Health Perspectives·Brian L GulsonGraham Vimpani
Nov 12, 2015·The Science of the Total Environment·Olanrewaju BelloZhaomin Dong
Aug 5, 2000·International Journal of Occupational and Environmental Health·J LaDou
Nov 6, 2009·International Journal of Occupational and Environmental Health·Ananya RoyKalpana Balakrishnan
Sep 27, 2005·The Science of the Total Environment·Vikram NichaniLuke P Naeher
Oct 24, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C YazbeckA-L Barbéry-Courcoux
Feb 11, 2005·Journal of Occupational Health·Marek Jakubowski, Malgorzata Trzcinka-Ochocka
Jan 24, 2009·Environmental Toxicology·Maqusood AhamedMohd K J Siddiqui
Dec 14, 2011·Paediatric and Perinatal Epidemiology·Jianghong LiuHerbert Needleman
Aug 15, 2000·American Journal of Industrial Medicine·A LeroyerJ M Haguenoer

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