Biological plywood film formation from para-nematic liquid crystalline organization

Soft Matter
Oscar F Aguilar Gutierrez, Alejandro D Rey

Abstract

In vitro non-equilibrium chiral phase ordering processes of biomacromolecular solutions offer a systematic and reproducible way of generating material architectures found in Nature, such as biological plywoods. Accelerated progress in biomimetic engineering of mesoscopic plywoods and other fibrous structures requires a fundamental understanding of processing and transport principles. In this work we focus on collagen I based materials and structures to find processing conditions that lead to defect-free collagen films displaying the helicoidal plywood architecture. Here we report experimentally-guided theory and simulations of the chiral phase ordering of collagen molecules through water solvent evaporation of pre-aligned dilute collagen solutions. We develop, implement and a posteriori validate an integrated liquid crystal chiral phase ordering-water transport model that captures the essential features of spatio-temporal chiral structure formation in shrinking film domains due to directed water loss. Three microstructural (texture) modes are identified depending on the particular value of the time-scale ratio defined by collagen rotational diffusion to water translational diffusion. The magnitude of the time scale ratio provid...Continue Reading

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Citations

Feb 21, 2018·Biomaterials Science·Hau Van DuongThanh-Dinh Nguyen
Sep 17, 2020·Nature Communications·Sayyed Ahmad KhademAlejandro D Rey
Oct 12, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Martin J PospisilMicah J Green
Apr 21, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Martin J PospisilMicah J Green
Sep 19, 2019·The Journal of Physical Chemistry. B·Oscar M Matus Rivas, Alejandro D Rey
Jan 24, 2019·The Journal of Physical Chemistry. B·Oscar M Matus Rivas, Alejandro D Rey

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