PMID: 3750350Jan 1, 1986Paper

Biological properties of Pyrularia thionin prepared from nuts of Pyrularia pubera

Toxicon : Official Journal of the International Society on Toxinology
G E EvettL P Vernon

Abstract

Pyrularia thionin is a 47 amino acid basic peptide which resembles wheat purothionin and mistletoe viscotoxin. It is toxic to mice, with an LD50 of 1.5 mg/kg body weight and is cytotoxic to tumor and normal cells in culture, with ID50 values ranging from 0.62 to 17 micrograms/ml. Against seven bacterial species it was toxic only to Micrococcus luteus. The toxin did not protect mice against transplanted B16 melanoma, nor did it show any mitogenic activity with mouse spleen lymphocytes.

References

Apr 1, 1985·Archives of Biochemistry and Biophysics·L P VernonW R Gray
May 15, 1970·Experientia·J NienhausF Vester
May 1, 1981·European Journal of Biochemistry·L CarrascoF García-Olmedo
Oct 1, 1980·Hoppe-Seyler's Zeitschrift für physiologische Chemie·J KonopaM Lewandowska-Gumieniak

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Citations

Jul 1, 1995·Plant Molecular Biology·S B Milligan, C S Gasser
Oct 1, 1994·Plant Molecular Biology·D E Florack, W J Stiekema
Jan 1, 1989·Toxicon : Official Journal of the International Society on Toxinology·V R Osorio e CastroL P Vernon
Jan 1, 1990·Toxicon : Official Journal of the International Society on Toxinology·C K AngerhoferL P Vernon
Jul 1, 1992·Toxicon : Official Journal of the International Society on Toxinology·L P Vernon, A Rogers
Dec 1, 1992·Toxicon : Official Journal of the International Society on Toxinology·A M JuddR M MacLeod
Nov 1, 1992·Toxicon : Official Journal of the International Society on Toxinology·W S FrackiL P Vernon
Jul 1, 1994·Toxicon : Official Journal of the International Society on Toxinology·W HuangJ D Bell
Jan 8, 1999·Biochimica Et Biophysica Acta·G M SteinA Büssing
Aug 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J EvansL P Vernon
Jan 24, 1998·Journal of Biomolecular Structure & Dynamics·T K KumarC Yu
Jun 15, 1991·European Journal of Biochemistry·G Schrader, K Apel
May 24, 2011·Clinical & Developmental Immunology·Matteo BordignonMauro Alaibac
Feb 21, 2002·Biochimica Et Biophysica Acta·Alexandre CoulonAndre Lopez

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