Biological properties of streptococcal cell-wall particles. I. Determinants of the chronic nodular lesion of connective tissue.

Journal of Bacteriology
J H Schwab

Abstract

Schwab, John H. (University of North Carolina, Chapel Hill). Biological properties of streptococcal cell-wall particles. I. Determinants of the chronic nodular lesion of connective tissue. J. Bacteriol. 90:1405-1411. 1965.-The capacity of cell-wall fragments to induce a chronic remittent nodular lesion after a single injection into rabbit skin varies qualitatively as well as quantitatively among the streptococci. This variation among strains is the result of a summation of several properties of the bacterial cell, some intrinsic and others extrinsic to the cell-wall structure. With some species, the inability to produce this lesion may be related to the susceptibility of cell walls to lysozyme. Other factors defined in this paper include production of hyaluronidase, and association of the cell walls with a component which can affect the interval between injection and appearance of the nodules, called the latent time. Separation of cell-wall fragments from more soluble cell material by centrifugation results in a shorter latent time. Addition of the soluble supernatant fraction back to the cell walls prolongs the latent time and increases the area of lesion involvement. This latter effect is due to a spreading factor present in ...Continue Reading

Citations

Jan 1, 1987·Scandinavian Journal of Rheumatology. Supplement·F Fantini
Jan 1, 1971·Acta Pathologica Et Microbiologica Scandinavica. Section B: Microbiology and Immunology·S M Helgeland, A Grov
Jul 1, 1975·Journal of Periodontology·G D Lange, L E Folke
Jan 1, 1972·Virchows Archiv. A: Pathology. Pathologische Anatomie·W SchachenmayrO Haferkamp
Mar 1, 1970·Infection and Immunity·J M Jones, J H Schwab
Jan 1, 1967·Journal of Bacteriology·G S SchusterA N Bahn
Mar 1, 1974·Bacteriological Reviews·E N Fox
Nov 1, 1967·Journal of Bacteriology·J H Schwab, S H Ohanian
Jul 25, 2000·Clinical Microbiology Reviews·M W Cunningham
Aug 1, 1978·Seminars in Arthritis and Rheumatism·N M Hadler, D A Granovetter
Oct 14, 1966·Science·W J Cromartie, J G Craddock

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