Biological Rhythm and Bipolar Disorder: Twelve-Month Follow-Up of a Randomized Clinical Trial

The Journal of Nervous and Mental Disease
Taiane de Azevedo CardosoKaren Jansen

Abstract

The objective was to evaluate the effect of psychoeducation on biological rhythm and in the reduction of depressive, anxious, and manic symptoms at 12 months' follow-up. This was a randomized clinical trial with young adults aged 18 to 29 years, diagnosed with bipolar disorder. Biological rhythm was assessed with the Biological Rhythm Interview Assessment in Neuropsychiatry (BRIAN). Participants were randomized for combined intervention (psychoeducation plus medication) or treatment-as-usual (medication alone). The sample consisted of 61 patients (29 TAU; 32 combined intervention). Although it failed to separate by a marginal difference, the combined intervention seems to be more effective than TAU in relation to improvement of depressive symptoms at post-intervention (p = 0.074) and regulation of sleep/social domain at 6 months' follow-up (p = 0.057). Improvement of depressive symptoms as well as regulation of sleep and social activities are known to prevent episode onset and thus improve long-term outcomes.

References

Sep 1, 1989·Archives of General Psychiatry·J Finkelstein
Dec 1, 1967·The British Journal of Social and Clinical Psychology·M Hamilton
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON
Aug 23, 2005·Revista de saúde pública·Aluísio J D Barros, Cesar G Victora
Sep 3, 2005·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J A A VilelaS R Loureiro
May 20, 2008·Journal of Affective Disorders·F ColomJ Scott
Feb 24, 2009·Journal of Affective Disorders·Larriany Maria Falsin GiglioFlávio Kapczinski
Sep 18, 2009·Journal of Psychiatric Research·Larriany M GiglioFlávio Kapczinski
Nov 9, 2010·Journal of Affective Disorders·Karen JansenRicardo Azevedo da Silva
Feb 10, 2012·Journal of Affective Disorders·Fatma Eker, Sirin Harkın
Sep 11, 2012·Journal of Affective Disorders·Karen JansenRicardo Azevedo da Silva
Dec 19, 2012·Journal of Affective Disorders·Karen JansenRicardo Azevedo da Silva
Dec 21, 2012·International Journal of Group Psychotherapy·Christian G BouwkampP M Judith Haffmans
Sep 18, 2013·Current Psychiatry Reports·Rébecca RobillardIan B Hickie
Feb 7, 2014·The Journal of Clinical Psychiatry·Robert Gonzalez
Jan 1, 2013·International Journal of Bipolar Disorders·Adriane R RosaEduard Vieta
Jan 27, 2015·Comprehensive Psychiatry·Jennifer B LevinMartha Sajatovic

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Citations

Aug 5, 2015·Journal of Affective Disorders·Augusto Duarte FariaKaren Jansen
Feb 18, 2017·The British Journal of Psychiatry : the Journal of Mental Science·Mary Lou ChattertonCathrine Mihalopoulos
Dec 6, 2019·The International Journal of Neuropsychopharmacology·Konstantinos N FountoulakisHans Jurgen Moeller
Mar 4, 2019·Current Psychiatry Reports·Alexandra K Gold, Gustavo Kinrys

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