Biological therapy of salivary duct carcinoma

The Journal of Laryngology and Otology
M Nashed, R J Casasola

Abstract

The incidence of human epidermal growth factor receptor 2 positivity in salivary duct carcinoma ranges from 25 to 100 per cent and is associated with a poor outcome. Salivary duct carcinoma has significant pathological similarities to ductal carcinoma of the breast. A 49-year-old man developed lung and liver metastasis a few months after surgery and adjuvant radiotherapy for salivary duct carcinoma of the parotid gland. There was no response to palliative chemotherapy with doxorubicin. We followed the biological model of breast cancer, whereby two-thirds of human epidermal growth factor receptor 2 positive patients respond to a combination of docetaxel and human epidermal growth factor receptor 2 blocker (trastuzumab). A durable, complete response was achieved with this combination. A rationalised treatment approach targeting the biological characteristics of salivary duct carcinoma had proven successful.

References

Dec 1, 1994·Human Pathology·C R De Potter
Dec 3, 2003·Journal of Clinical Pathology·A EtgesV C Araújo
May 20, 2004·Journal of the National Cancer Institute·Mark D PegramDennis J Slamon
Jun 7, 2006·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Nobuaki SatoMorihiko Kimura

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Citations

Apr 13, 2012·The Journal of Laryngology and Otology·D T H WeeP J Bradley
May 9, 2012·Head & Neck Oncology·Aymen LaghaAmel Mezlini
Feb 23, 2013·The Oncologist·Sewanti A LimayeRobert I Haddad
May 27, 2014·Oral Oncology·Göran StenmanMattias K Andersson
Aug 5, 2014·American Journal of Otolaryngology·Nobuko YamamotoMasato Fujii
Mar 23, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Elina SalovaaraAntti A Mäkitie
Jun 17, 2010·Der Pathologe·M GrünbaumC Loddenkemper
Jul 15, 2015·Oncology Letters·Xiaofeng HuangRunzhi Deng
Feb 1, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jong Sil LeeJi Hyun Seo
Jun 15, 2011·Pathology·Till Sebastian ClauditzWaldemar Wilczak
Apr 3, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Juliana LemoundKais Hussein
Jun 2, 2015·Auris, Nasus, Larynx·Myung Woul HanSang Yoon Kim
Aug 20, 2014·Case Reports in Oncological Medicine·Muhammad Shahid IqbalJosef Kovarik
Feb 21, 2014·International Journal of Clinical Oncology·Tatsuo MasubuchiToshitaka Nagao
Jun 13, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Naseem GhazaliJoshua E Lubek
Aug 27, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Nicole C SchmittSeungwon Kim
Mar 23, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Heidy C J JaspersCarla M L van Herpen
Sep 27, 2014·Nihon Jibiinkoka Gakkai kaiho·Fukuichiro IguchiNorihiko Murai
Jul 16, 2013·The American Journal of Surgical Pathology·Christopher C GriffithSimion I Chiosea
Mar 23, 2018·International Journal of Clinical Oncology·Akira NishikadoYoshinobu Hirose
Feb 25, 2017·Archives of Pathology & Laboratory Medicine·Christopher C GriffithKelly R Magliocca
May 23, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ann-Jean C C BeckWillem M C Klop
Feb 28, 2015·The American Journal of Surgical Pathology·Simion I ChioseaMarina N Nikiforova
Apr 15, 2015·The American Journal of Surgical Pathology·Lindsay WilliamsSimion I Chiosea
Nov 29, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Valentina NardiDora Dias-Santagata
Feb 3, 2021·Surgical Pathology Clinics·Doreen PalsgroveSaad A Khan
Mar 12, 2021·Frontiers in Oncology·Takayoshi SuzukiAkihiro Homma

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