PMID: 1726074Dec 1, 1991

Biologically active constituents of Magnolia salicifolia: inhibitors of induced histamine release from rat mast cells

Chemical & Pharmaceutical Bulletin
T TsurugaU Sankawa

Abstract

The extracts of the flower buds of Magnolia salicifolia showed remarkable anti-allergy effects in passive cutaneous anaphylaxis (PCA) test. The bioactive constituents of this medicinal drug were isolated by monitoring their activities with an in vitro bioassay system measuring inhibitory effects on induced histamine release from rat mast cells. Of the ten isolated compounds magnosalicin is a new compound of neolignan structure. In addition to the isolated compounds samples of coumarins and lignans were evaluated their biological activities with the in vitro bioassay.

Citations

Feb 1, 2011·Pharmacology & Therapeutics·Young-Jung LeeJin Tae Hong
Jun 9, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wei-Sheng FengKai Song
Jul 7, 2001·Archives of Pharmacal Research·T Y ShinE J Lee
Feb 5, 2002·Biological & Pharmaceutical Bulletin·Hisae OkuKyoko Ishiguro
Sep 19, 2002·Phytotherapy Research : PTR·N BackhouseJ L López-Pérez
Oct 2, 2008·Biological & Pharmaceutical Bulletin·Noriko HirataHideaki Matsuda
Sep 5, 2017·Chemical & Pharmaceutical Bulletin·Thi Tuyet Mai NguyenJeong Ah Kim
Sep 1, 2018·Comprehensive Reviews in Food Science and Food Safety·Daniel M GrochowskiMichał Tomczyk

Related Concepts

Magnosalicin
Plant Extracts, Chinese
Tetrahydrofurans
Histamine Release
Mast Cell
Passive Cutaneous Anaphylaxis
August Rats
Neolignans

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