PMID: 8588867Jan 1, 1996Paper

Biologically active flavonoids and terpenoids from Egletes viscosa

Phytochemistry
M A LimaM T Gambardela

Abstract

The steam volatile components from the hexane extract of dried flower buds of Egletes viscosa were identified by gas chromatography-mass spectrometry as trans-carvyl acetate, cis-carvyl acetate, sabinyl acetate, verbenyl acetate, cyclopentaethylidene, geranyl acetate and 5-methylfuranone, and trans-pinocarvyl acetate (major component). From the non-volatile residue, centipedic acid and a novel clerodane diterpene, 12-acetoxy-hawtriwaic acid lactone, were isolated. From the ethanol extract, ternatin (4',5-dihidroxy-3,3',7,8-tetramethoxyflavone), was isolated. Ternatin showed anti-inflammatory, hepatoprotection and gastroprotection properties, and, according to the NCI protocols, it showed moderate activity against HIV. The diterpenes showed antispasmodic activity. Structure determination of these secondary metabolites was accomplished by spectrometric methods, including 2D NMR, chemical interconversion and X-ray crystallographic analysis.

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Citations

May 18, 2000·Phytotherapy Research : PTR·C PessoaA Leyva
Jul 2, 2008·Biological & Pharmaceutical Bulletin·Marjorie Moreira GuedesVietla Satyanarayana Rao
Mar 1, 1997·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·M F SouzaE R Silveira
Sep 15, 2012·Chemical & Pharmaceutical Bulletin·Matsutake HigaToshimasa Suzuka
Apr 27, 1999·The Journal of Pharmacy and Pharmacology·M F SouzaV S Rao
Nov 8, 2016·Natural Product Research·Sony GeorgeSabulal Baby
Jun 8, 2013·Acta Cirúrgica Brasileira·José Ulisses de Souza MeloPaulo Roberto Leitão Vasconcelos
Aug 3, 2011·Acta Cirúrgica Brasileira·Sergio Botelho GuimarãesPaulo Roberto Leitão de Vasconcelos
Mar 17, 2004·Phytotherapy Research : PTR·Milena Morais VieiraRonaldo A Ribeiro

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