Biologically active oligostilbenes from the stems of Vatica mangachapoi and chemotaxonomic significance

Natural Product Research
Shou-Yuan WuXiao-Ping Song

Abstract

Phytochemical investigation of the stems of Vatica mangachapoi (Dipterocarpaceae) led to the isolation and structural elucidation of twenty-seven oligostilbenes (1-27), including a new natural compound 1. The structure of 1 was elucidated on the basis of spectroscopic analyses including NMR, MS and ECD data, and the known compounds were identified by comparisons with those reported in the literature. The absolute configuration of 1 was first time determined by a combination of NOESY spectrum and quantum chemical computation. Among of isolates were tested for their anti-osteoporosis and anti-HIV-1 activities in vitro by the MTT method. Moreover, the chemotaxonomic significance of these compounds was summarised.

References

Feb 1, 1990·Chemical & Pharmaceutical Bulletin·S KitanakaI H Kim
Apr 17, 1998·Journal of Natural Products·J R DaiM R Boyd
May 23, 2000·Phytochemistry·T TanakaV Chelladurai
Nov 26, 2002·Journal of Natural Products·Joanna R Zgoda-PolsJohn R Porter
Mar 1, 2003·Journal of Natural Products·Hong-Jie ZhangHarry H S Fong
Dec 3, 2005·Zeitschrift Für Naturforschung. C, a Journal of Biosciences· SahidinSjamsul A Achmad
Oct 31, 2006·Fitoterapia· MuhtadiEmilio L Ghisalberti
Jun 6, 2009·Journal of Agricultural and Food Chemistry·Hui-Ming GeRen-Xiang Tan
Jun 26, 2009·Natural Product Reports·Tao ShenHong-Xiang Lou
Aug 26, 2010·Journal of Natural Products·Naohito AbeMunekazu Iinuma
Oct 12, 2010·Chemical & Pharmaceutical Bulletin·Tetsuro ItoMunekazu Iinuma
Apr 7, 2011·Chemical & Pharmaceutical Bulletin·Naohito AbeMunekazu Iinuma
Jul 28, 2011·Angewandte Chemie·Scott A SnyderSteven P Breazzano
Jan 21, 2012·Journal of Natural Medicines·Toshio MorikawaOsamu Muraoka
May 26, 2012·Planta medica·Tong YanHui Ming Ge
Aug 1, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Norhayati MuhammadWan A Yaacob

❮ Previous
Next ❯

Citations

May 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ramandeep KaurDinesh Kumar

❮ Previous
Next ❯

Methods Mentioned

BETA
circular dichroism
column chromatography

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.