Biologically active quinoline and quinazoline alkaloids part II

Medicinal Research Reviews
Xiao-Fei ShangKuo-Hsiung Lee

Abstract

To follow-up on our prior Part I review, this Part II review summarizes and provides updated literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009-2016, together with the biological activity and the mechanisms of action of these classes of natural products. Over 200 molecules with a broad range of biological activities, including antitumor, antiparasitic and insecticidal, antibacterial and antifungal, cardioprotective, antiviral, anti-inflammatory, hepatoprotective, antioxidant, anti-asthma, antitussive, and other activities, are discussed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.

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Citations

Sep 1, 2020·Biotechnology and Applied Biochemistry·Wenle WangFeng Feng
Nov 11, 2020·Natural Product Reports·Jeffrey D RudolfZining Li
Aug 14, 2020·Chemistry : a European Journal·Yuanyuan WangFrederik Diness
Jun 8, 2021·Acta Crystallographica Section B, Structural Science, Crystal Engineering and Materials·Akmaljon G TojiboevSirojiddin Z Mirzaev
Jul 23, 2021·Journal of the American Chemical Society·Jingjing XieX Peter Zhang
Nov 30, 2021·Journal of Agricultural and Food Chemistry·Ren-Xuan WangYing-Qian Liu

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