Biologically plausible neural computation

Bio Systems
G Bugmann

Abstract

The function of a neuron can be described simultaneously at several levels of abstraction. For instance, a spike train represents the result of a computation done by a single neuron with its inputs, but it also represents the result of a complex function realized by the network in which the neuron is embedded. When models of large parts of the brain are considered, it may be desirable to use computational modules operating at a very abstract level. However, it is shown here that abstract neural functions depend on detailed features of the single neuron model used in the network reproducing the abstract function. Examples are given of the multiplicative function, motion detection, short-term memory and timing. All these operations rely on one or another feature of the extended Leaky Integrate-and-Fire neuron used in this paper, e.g. probabilistic synapses, post-synaptic currents modelled with alpha functions or partial reset of the somatic membrane. Consequently it is suggested that neural modelling at an abstract level does not obviate the need for a clear statement on the nature of the underlying model of biological neuron. In that sense, not many abstract functions are convincingly grounded, not even the standard formal neuro...Continue Reading

References

Jun 28, 1991·Science·W BialekD Warland
Jan 1, 1985·Neuroscience Research. Supplement : the Official Journal of the Japan Neuroscience Society·N Franceschini
Nov 1, 1973·Kybernetik·T Poggio, W Reichardt
Dec 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M Corbetta

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Citations

Oct 24, 2003·Brain and Cognition·Arash Hadipour Niktarash
Jan 14, 1999·Bio Systems·G Bugmann
Jan 6, 2006·Artificial Life·Keren Saggie-WexlerEytan Ruppin
Aug 30, 2002·Psychonomic Bulletin & Review·I E Dror, D P Gallogly
Jul 19, 2015·Journal of Theoretical Biology·R P MorseN G Stocks
Apr 20, 2007·Osteoarthritis and Cartilage·Z LiS Grad
Jul 21, 2010·Journal of Neural Engineering·Bradley E LosavioPeter Saggau
Apr 13, 2012·Journal of Neurophysiology·Jason F HunzingerRobert C Froemke
Oct 2, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Lindi TanXiao-Fang Yu
Jun 14, 2019·International Journal of Neural Systems·Yuki TodoKazuya Yamashita

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