Biologically synthesized ZnS quantum dots as fluorescent probes for lead (II) sensing.

Luminescence : the Journal of Biological and Chemical Luminescence
Jaya Mary JacobGayathri G Kurup

Abstract

This manuscript presents a robust strategy for selective Pb(II) sensing based on a fluorescence turn-off mechanism using ZnS quantum dots (QDs) biosynthesized using Aspergillus sp. The biogenic nanoprobe displayed marked sensing efficiency in the presence of Pb ions over concentration ranges from 5 to 100 μM with limits of detection of around 2.45 μM. Performance optimization studies revealed that the maximum fluorescence quenching efficiency was obtained in the presence of [ZnS NPs] at 4 mg/ml, and alkaline pH of 10 recorded under stable ambient temperature for approximately 5 min for the quenching process. Advanced morphological analysis indicated that the bio-sensing mechanism was essentially a surface-based phenomenon in which the Pb ions were in very close proximity to the QDs and formed stable ground-state Pb-ZnS complexes, resulting in a quenched fluorescence of the QDs. Simultaneously, a larger fraction of Pb ions interacted via collisions with the excited ZnS QDs and resulted in an effective energy transfer from the excited QDs to the Pb ions, therefore resulting in an obvious decrease in QD fluorescence. These insights were well supported by theoretical analysis using Stern-Volmer plots and sphere-of-action models.

References

Aug 31, 2000·Nature Structural Biology·P R Selvin
Oct 7, 2004·Analytical Biochemistry·Wei LianShouguang Jin
May 8, 2010·Journal of the American Chemical Society·Huimin ChenWatt W Webb
Sep 20, 2011·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Ahmed S Al-KadyEl-Zeiny M Ebeid
Nov 18, 2018·Bulletin of Environmental Contamination and Toxicology·Muhammad Iftikhar KhanMuhammad Khisroon
Aug 29, 2019·Frontiers in Microbiology·Carla Gallardo-BenaventeAndrés Quiroz
Sep 25, 2019·Materials Science & Engineering. C, Materials for Biological Applications·Cai ShiZhanhu Guo
Nov 23, 2019·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Zhezhu NanRunguang Sun
Mar 7, 2020·Analytica Chimica Acta·Shu ZhangLidong Wu
Mar 15, 2020·Advances in Colloid and Interface Science·Sulaxna Pandey, Dhananjay Bodas

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Citations

Oct 4, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mohamed Abdel-SalamKwang-Hyun Baek

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