PMID: 2487796Oct 1, 1989Paper

Biology and space medicine. New prospects for internal medicine

Annali italiani di medicina interna : organo ufficiale della Società italiana di medicina interna
G TallaridaF Iellamo

Abstract

Most of the functional problems astronauts may suffer during and after long-term space missions are mainly associated with the reduction of the gravity force which causes a central fluid shift and a redistribution of the blood flow. Blood volume centralization induces a rapid increase in diuresis with elimination of consistent amounts of water and electrolytes which leads to a reduction of cardiac output, body fluid and to a hypodynamic state of the cardiovascular system. The effects of micro-gravity on skeletal and muscular systems are quite severe causing rapid bone demineralization, especially in the spine and lower extremities, and hypotrophy of the muscular masses. Micro-g also appears to determine cellular and molecular modifications with inhibition of the immune system, hematopoiesis and resistance to infections. Orthostatic intolerance, with feeling sick, instability and sometimes syncope, is characteristically observed after the return to earth due to a remarkable fluid shift in the lower part of the body and an acute reduction in blood flow to the brain. Physical exercise may play an important role among the countermeasures proposed to reduce most of the cardiovascular and musculo-skeletal effects of micro-g. Furtherm...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

La Presse médicale
A Pavy-Le-TraonC Gharib
Journal of the British Interplanetary Society
Adam Hawkey
Interdisciplinary Science Reviews : ISR
Adam Hawkey
European Journal of Applied Physiology
G Antonutto, P E di Prampero
© 2022 Meta ULC. All rights reserved